⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818638 | 0.78 | MGLL (0.55) | — | |
| SCHEMBL21087586 | 0.78 | MGLL (0.55) | — | |
| SCHEMBL22773554 | 0.77 | — | — | |
| SCHEMBL1418058 | 0.74 | — | — | |
| SCHEMBL20195366 | 0.72 | MGLL (0.55) | — | |
| SCHEMBL11824386 | 0.72 | MGLL (0.48) | — | |
| SCHEMBL12195318 | 0.70 | MGLL (0.78) | — | |
| SCHEMBL3719431 | 0.70 | ANPEP (0.43) | — | |
| SCHEMBL21686974 | 0.70 | MGLL (0.46) | — | |
| SCHEMBL8843845 | 0.70 | MGLL (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |