Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818638 | 0.85 | MGLL (0.55) | MGLLFAAHPHGDHALDH1A1ALDH2 | |
| SCHEMBL11824386 | 0.78 | MGLL (0.48) | MGLLFAAHPHGDHALDH1A1ALDH2 | |
| SCHEMBL21686974 | 0.76 | MGLL (0.46) | MGLLFAAHPHGDHALDH1A1ALDH2 | |
| SCHEMBL11823675 | 0.74 | MGLL (0.44) | MGLLFAAHPHGDHALDH1A1ALDH2 | |
| SCHEMBL10768756 | 0.74 | MGLL (0.39) | MGLLALDH1A1 | |
| SCHEMBL21087586 | 0.74 | MGLL (0.55) | MGLLFAAHPHGDHALDH1A1ALDH2 | |
| SCHEMBL8329289 | 0.70 | — | — | |
| SCHEMBL1418058 | 0.70 | — | — | |
| SCHEMBL28561971 | 0.69 | SMN1; SMN2 (0.41) | MGLL | |
| Hydrochloric Acid SCHEMBL27550956 | 0.66 | KDM4E (0.44) | MGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |