SCHEMBL8329321

SCHEMBL8329321

CC(C)(C)[Si](C)(C)OCC[CH]CN

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14244960 0.87 DUT (0.33) DUT
SCHEMBL4702166 0.81 DUT (0.31) DUT
SCHEMBL4059577 0.80 DUT (0.33) DUT
SCHEMBL18377988 0.78 DUT (0.33) DUT
SCHEMBL333169 0.75 DUT (0.34) DUT
SCHEMBL1561882 0.75 DUT (0.38) DUT
SCHEMBL14907555 0.74 DUT (0.32) DUT
SCHEMBL573170 0.74 DUT (0.35) DUT
SCHEMBL11580466 0.74 DUT (0.42) DUT
SCHEMBL16829819 0.73 TSHR (0.42) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0944629-A1 BIARYL-PYRIDOQUINAZOLINONE DERIVATIVES AS ANTI-CANCER AGENTS American Cyanamid Company (US) 1999-09-29 EP disclosed
WO-1998023616-A1 BIARYL-PYRIDOQUINAZOLINONE DERIVATIVES AS ANTI-CANCER AGENTS AMERICAN CYANAMID COMPANY (US) 1998-06-04 WO disclosed