SCHEMBL4059577

SCHEMBL4059577

C=CCCO[Si](C)(C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.33
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14244960 0.88 DUT (0.33) DUT
SCHEMBL4455945 0.86 DUT (0.37) DUTTSHR
SCHEMBL592575 0.85 TSHR (0.38) DUTTSHR
SCHEMBL18377988 0.83 DUT (0.33) DUT
SCHEMBL17732227 0.83 TSHR (0.41) DUTTSHR
SCHEMBL1931760 0.83 TSHR (0.41) DUTTSHR
SCHEMBL30895945 0.83 TSHR (0.41) DUTTSHR
SCHEMBL2245848 0.83 TSHR (0.41) DUTTSHR
SCHEMBL4702166 0.82 DUT (0.31) DUT
SCHEMBL8329321 0.80 DUT (0.30) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608926-A1 HOT MELT ADHESIVE COMPRISING SILOXIDE-FUNCTIONALIZED POLYOLEFINS SABIC Global Technologies B.V. (NL) 2025-09-03 EP claimed
CN-119948125-A Hot melt adhesive comprising siloxy functionalized polyolefin SABIC环球技术有限责任公司 2025-05-06 CN claimed
WO-2024088806-A1 HOT MELT ADHESIVE COMPRISING SILOXIDE-FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-05-02 WO claimed
US-20260028350-A1 TOXIN MOLECULE SUITABLE FOR ANTIBODY-DRUG CONJUGATE MINGHUI PHARMACEUTICAL HANGZHOU LTD (CN) 2026-01-29 US disclosed
EP-4608926-A1 HOT MELT ADHESIVE COMPRISING SILOXIDE-FUNCTIONALIZED POLYOLEFINS SABIC Global Technologies B.V. (NL) 2025-09-03 EP disclosed
EP-4563578-A1 TOXIN MOLECULE SUITABLE FOR ANTIBODY-DRUG CONJUGATE Minghui Pharmaceutical (Hangzhou) Limited (CN) 2025-06-04 EP disclosed
CN-119948125-A Hot melt adhesive comprising siloxy functionalized polyolefin SABIC环球技术有限责任公司 2025-05-06 CN disclosed
CN-119585281-A Toxin molecules suitable for antibody-drug conjugates 明慧医药(杭州)有限公司 2025-03-07 CN disclosed
WO-2025002626-A1 HOT MELT ADHESIVES BASED ON BLENDS COMPRISING NON- FUNCTIONALIZED AND FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-01-02 WO disclosed
WO-2025002627-A1 HOT MELT ADHESIVES BASED ON BLENDS COMPRISING NON-FUNCTIONALIZED AND FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-01-02 WO disclosed
US-20240317917-A1 METHODS FOR HYDROAMINOALKYLATION OF OLEFINS AND GROUP 4 METAL COMPLEXES USEFUL IN SUCH METHODS UNIV BRITISH COLUMBIA (CA) 2024-09-26 US disclosed
US-20020032206-A1 Pharmaceutical compositions for prevention and treatment of central nervous system disorders CALDWELL WILLIAM SCOTT (US) 2002-03-14 US disclosed
EP-0900200-A1 PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS R.J. REYNOLDS TOBACCO COMPANY (US) 1999-03-10 EP disclosed
US-5830885-A BIOLOGICAL ANTIGROWTH AGENT THE JOHNS HOPKINS UNIVERSITY (US) 1998-11-03 US disclosed
WO-1997040011-A1 PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS R. J. REYNOLDS TOBACCO COMPANY (US) 1997-10-30 WO disclosed
EP-0688336-B1 PEPTIDE BORONIC ACID DERIVATIVES HAVING PROTEASE INHIBITING ACTIVITY CIBA GEIGY AG (CH) 1997-05-28 EP disclosed
US-5616716-A (3-(5-ethoxypyridin)yl)-alkenyl 1 amine compounds TARGACEPT, INC. 1997-04-01 US disclosed
EP-0688336-A1 PEPTIDE BORONIC ACID DERIVATIVES HAVING PROTEASE INHIBITING ACTIVITY SANDOZ LTD (CH) 1995-12-27 EP disclosed
WO-1994020526-A1 PEPTIDE BORONIC ACID DERIVATIVES HAVING PROTEASE INHIBITING ACTIVITY SANDOZ LTD. (CH) 1994-09-15 WO disclosed
EP-0396364-A2 Novel vinyl carbonate and vinyl carbamate contact lens material monomers BAUSCH & LOMB INCORPORATED (US) 1990-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020032206-A1 Pharmaceutical compositions for prevention and treatment of central nervous system disorders PMP22, AANAT, CHAT DUT 4119/4885CA2 4571/4885CA9 4762/4885
US-20260028350-A1 TOXIN MOLECULE SUITABLE FOR ANTIBODY-DRUG CONJUGATE ANTXR2, CCR8, FCGRT DUT 1986/4885CA2 149/4885CA9 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.