Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324824 | 0.91 | GAA (0.50) | GAASMN1; SMN2CSF1RNPC1ALDH1A1 | |
| SCHEMBL8329171 | 0.90 | MAPT (0.45) | SMN1; SMN2MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL8325775 | 0.90 | MAPT (0.56) | GAASMN1; SMN2MAPTNPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8330855 | 0.89 | MAPT (0.56) | GAASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL8328001 | 0.88 | MELK (0.47) | MAPTPAX8PIK3CAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8330455 | 0.88 | MAPT (0.55) | GAASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL8327531 | 0.87 | MAPT (0.43) | MAPT | |
| SCHEMBL8329163 | 0.86 | GAA (0.51) | GAASMN1; SMN2CSF1RNPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9050309 | 0.86 | MAPT (0.42) | MAPTSLC2A1 | |
| SCHEMBL8329154 | 0.85 | MAPT (0.42) | SMN1; SMN2MAPTNPC1NPSR1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |