Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329323 | 0.91 | GAA (0.47) | GAASMN1; SMN2CSF1RALDH1A1NPC1 | |
| SCHEMBL8325581 | 0.91 | HDAC3 (0.43) | GAASMN1; SMN2PDE4BPOLBKMT2A | |
| SCHEMBL8329163 | 0.90 | GAA (0.51) | GAASMN1; SMN2CSF1RALDH1A1NPC1 | |
| SCHEMBL8328847 | 0.86 | PDE4B (0.56) | GAASMN1; SMN2ALDH1A1HTTNPSR1 | |
| SCHEMBL8325775 | 0.81 | MAPT (0.56) | GAASMN1; SMN2ALDH1A1NPC1HTT | |
| SCHEMBL8329171 | 0.81 | MAPT (0.45) | SMN1; SMN2ALDH1A1NPC1RAB9ANPSR1 | |
| Hydrochloric Acid SCHEMBL8330855 | 0.80 | MAPT (0.56) | GAASMN1; SMN2ALDH1A1NPC1HTT | |
| Hydrochloric Acid SCHEMBL8330455 | 0.79 | MAPT (0.55) | GAASMN1; SMN2ALDH1A1NPC1HTT | |
| SCHEMBL8327531 | 0.78 | MAPT (0.43) | EGFR | |
| SCHEMBL8328001 | 0.78 | MELK (0.47) | POLBKMT2APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |