Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869540 | 0.91 | MEN1 (0.46) | MEN1KMT2ADRD1ROCK2HSD17B10 | |
| SCHEMBL9559464 | 0.88 | HSD17B10 (0.47) | MEN1KMT2ADRD1ROCK2HSD17B10 | |
| SCHEMBL7497691 | 0.85 | POLB (0.56) | MEN1KMT2ADRD1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL9697856 | 0.83 | MEN1 (0.45) | MEN1KMT2ADRD1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9523368 | 0.83 | MEN1 (0.45) | MEN1KMT2ADRD1HSD17B10 | |
| SCHEMBL9727194 | 0.82 | TP53 (0.46) | MEN1KMT2AROCK2HSD17B10MAPT | |
| SCHEMBL9384977 | 0.81 | HSD17B10 (0.49) | MEN1KMT2ADRD1HSD17B10 | |
| SCHEMBL7505146 | 0.81 | HSD17B10 (0.59) | MEN1KMT2ADRD1THRBHSD17B10 | |
| SCHEMBL9523968 | 0.80 | HSD17B10 (0.48) | MEN1KMT2ADRD1HSD17B10 | |
| SCHEMBL9525676 | 0.80 | HSD17B10 (0.48) | MEN1KMT2ADRD1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943615-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1999-09-22 | — | — | EP | disclosed |