Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.72 |
| ▸ | XIAP | P98170 | 6/20 | 0.55 |
| ▸ | NPY1R | P25929 | 11/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330374 | 0.93 | GHSR (0.84) | GHSRXIAPNPY1R | |
| SCHEMBL7796087 | 0.87 | XIAP (0.58) | GHSRXIAPNPY1R | |
| SCHEMBL7438263 | 0.84 | GHSR (1.00) | GHSRXIAPNPY1R | |
| SCHEMBL7792149 | 0.83 | GHSR (1.00) | GHSRXIAPNPY1R | |
| SCHEMBL8329866 | 0.83 | GHSR (0.88) | GHSRXIAPNPY1R | |
| SCHEMBL7792445 | 0.83 | GHSR (0.87) | GHSRXIAPNPY1R | |
| SCHEMBL7794452 | 0.83 | GHSR (1.00) | GHSRXIAPNPY1R | |
| SCHEMBL8332812 | 0.82 | GHSR (0.80) | GHSRXIAPNPY1R | |
| SCHEMBL7791986 | 0.82 | GHSR (0.85) | GHSRXIAPNPY1R | |
| SCHEMBL8331781 | 0.82 | GHSR (0.86) | GHSRXIAPNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968924-A | HAVE THE ABILITY TO STIMULATE THE RELEASE OF NATURAL OR ENDOGENOUS GROWTH HORMONE; TREATMENT OF OBESITY, OSTEOPOROSIS | MERCK & CO., INC. (US) | 1999-10-19 | — | — | US | disclosed |
| WO-1994005634-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1994-03-17 | — | — | WO | disclosed |