SCHEMBL7796087

SCHEMBL7796087

CCC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccccc2-c2ccccc2CNC(=O)NC(C)C)C1=O

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
XIAP P98170 5/20 0.58
GHSR Q92847 3/20 0.56
NPY1R P25929 12/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7785883 0.92 GHSR (0.68) XIAPGHSRNPY1R
SCHEMBL8329408 0.87 GHSR (0.72) XIAPGHSRNPY1R
SCHEMBL7786019 0.82 GHSR (0.80) XIAPGHSRNPY1R
SCHEMBL7794451 0.82 GHSR (0.81) XIAPGHSRNPY1R
SCHEMBL7785880 0.82 GHSR (0.73) XIAPGHSRNPY1R
SCHEMBL7785735 0.82 GHSR (0.70) XIAPGHSRNPY1R
SCHEMBL7785844 0.81 GHSR (0.80) XIAPGHSRNPY1R
SCHEMBL7785886 0.81 GHSR (0.73) XIAPGHSRNPY1R
SCHEMBL8330374 0.81 GHSR (0.84) XIAPGHSRNPY1R
SCHEMBL7795496 0.81 GHSR (0.63) XIAPGHSRNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659179-B1 BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE MERCK & CO INC (US) 2001-11-21 EP disclosed