⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654467 | 1.00 | — | — | |
| SCHEMBL19730165 | 0.75 | — | — | |
| SCHEMBL8324768 | 0.75 | — | — | |
| SCHEMBL3696578 | 0.73 | — | — | |
| SCHEMBL11288135 | 0.67 | — | — | |
| SCHEMBL11287028 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL11287030 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL19120267 | 0.66 | — | — | |
| SCHEMBL14629631 | 0.62 | POLB (0.33) | — | |
| SCHEMBL18902422 | 0.62 | POLB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463162-B1 | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES | TORAY INDUSTRIES (JP) | 1994-05-11 | — | — | EP | claimed |
| US-5202447-A | Stereospecific | TORAY INDUSTRIES, INC. (JP) | 1993-04-13 | — | — | US | claimed |
| EP-0463162-A1 | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1992-01-02 | — | — | EP | claimed |
| JP-57144233-A | — | — | None | — | — | JP | disclosed |
| US-20070149481-A1 | N,n-bridged, nitrogen-substituted carbacyclic indolocarbazoles as protein kinase inhibitors | NAD AG (DE) | 2007-06-28 | — | — | US | disclosed |
| US-20070149481-A1 | N,n-bridged, nitrogen-substituted carbacyclic indolocarbazoles as protein kinase inhibitors | NAD AG (DE) | 2007-06-28 | — | — | US | disclosed |
| WO-2004048384-A1 | N,N-BRIDGED, NITROGEN-SUBSTITUTED CARBACYCLIC INDOLOCARBAZOLES AS PROTEIN KINASE INHIBITORS | NAD AG (DE) | 2004-06-10 | — | — | WO | disclosed |
| US-5420310-A | Anticoagulants, antiulcer, antiatherosclerosis agents formed in multistage reaction | TORAY INDUSTRIES, INC. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0463162-B1 | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES | TORAY INDUSTRIES (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5202447-A | Stereospecific | TORAY INDUSTRIES, INC. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0463162-A1 | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1992-01-02 | — | — | EP | disclosed |
| WO-1986007611-A1 | PROCESS FOR PREPARING 4-HYDROXYCYCLOPENT-2-EN-1-ONE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1986-12-31 | — | — | WO | disclosed |
| US-4564620-A | 5,6,7,-Trinor-4,8-inter-m-phenylene PGI2 derivatives and anti-ulcer, anti-thrombotic and anti-hypertensive pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0060640-B1 | 5,6,7-TRINOR-4,8-INTER-M-PHENYLENE PGI DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TORAY INDUSTRIES, INC. (JP) | 1985-11-13 | — | — | EP | disclosed |
| EP-0024943-B1 | 5,6,7-TRINOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TORAY INDUSTRIES, INC. (JP) | 1983-08-17 | — | — | EP | disclosed |
| EP-0060640-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1982-09-22 | — | — | EP | disclosed |
| JP-S57144233-A | CYCLOPENTENE DERIVATIVE | TORAY IND INC | 1982-09-06 | — | — | JP | disclosed |
| US-4301164-A | FOR USE AS ANTIULCER AGENTS, HYPOTENSIVE AGENTS, ANTITHROMBOSIC AGENTS | TORAY INDUSTRIES, INC. (JP) | 1981-11-17 | — | — | US | disclosed |
| EP-0024943-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI2 derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1981-03-11 | — | — | EP | disclosed |
| US-4001308-A | REACTION OF DIBROMO COMPOUND WITH METAL SALT OF ACETIC ACID | TEIJIN LIMITED (JA) | 1977-01-04 | — | — | US | disclosed |