SCHEMBL8329694

SCHEMBL8329694

C=CCc1ccc(C(=O)c2ccc(C(=O)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
LMNA P02545 2/20 0.59
SRD5A2 P31213 2/20 0.56
CNR2 P34972 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
MAPK1 P28482 1/20 0.45
HSD17B10 Q99714 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
ALOX12 P18054 1/20 0.44
PKM P14618 2/20 0.44
HTT P42858 2/20 0.44
ATM Q13315 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
HPGD P15428 1/20 0.44
NLRP1 Q9C000 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27475875 0.95 ALDH1A1 (0.53) ALDH1A1LMNASRD5A2CNR2CYP1A2
SCHEMBL1081804 0.90 CYP1A2 (0.47) ALDH1A1LMNASRD5A2CNR2CYP1A2
SCHEMBL8333338 0.85 ALDH1A1 (0.64) ALDH1A1LMNASRD5A2SMN1; SMN2PKM
SCHEMBL87997 0.84 ALDH1A1 (0.58) ALDH1A1CNR2CYP1A2CYP2D6MAPK1
SCHEMBL11568621 0.83 SRD5A2 (0.58) ALDH1A1LMNASRD5A2TP53TSHR
SCHEMBL474925 0.83 ALDH1A1 (0.57) ALDH1A1LMNASRD5A2HSD17B10SMN1; SMN2
SCHEMBL11649305 0.82 ALDH1A1 (0.56) ALDH1A1CNR2CYP1A2CYP2D6MAPK1
Sulfuric Acid SCHEMBL18686201 0.81 CNR2 (0.55) ALDH1A1CNR2CYP1A2CYP2D6MAPK1
SCHEMBL9737342 0.80 SRD5A2 (0.54) ALDH1A1SRD5A2SMN1; SMN2TP53CYP3A4
SCHEMBL778425 0.79 ALDH1A1 (0.44) ALDH1A1LMNASRD5A2CNR2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1206334-C Washing method PROCTER & GAMBLE (US) 2005-06-15 CN disclosed
CN-1440452-A Process for making solid cleaning compositions PROCTER & GAMBLE (US) 2003-09-03 CN disclosed
CN-1113953-C Detergent particle PROCTER & GAMBLE (US) 2003-07-09 CN disclosed
CN-1416460-A Detergent compsns. P & G CO (US) 2003-05-07 CN disclosed
CN-1105166-C Detergent composition PROCTER & GAMBLE (US) 2003-04-09 CN disclosed
CN-1094514-C Detergent containing heavy metal sequestrant and delayed release peroxyacid bleach system PROCTER & GAMBLE (US) 2002-11-20 CN disclosed
CN-1373180-A Washing method PROCTER & GAMBLE (US) 2002-10-09 CN disclosed
CN-1083001-C Detergent compositions comprising enzymes and delayed-release peroxyacid bleaching systems PROCTER & GAMBLE (US) 2002-04-17 CN disclosed
CN-1083000-C Detergent containing surfactant and delayed release enzyme PROCTER & GAMBLE (US) 2002-04-17 CN disclosed
CN-1337997-A Detergent tablet PROCTER & GAMBLE (US) 2002-02-27 CN disclosed
CN-1216525-A Cationic detergent compounds PROCTER & GAMBLE (US) 1999-05-12 CN disclosed
CN-1201485-A Detergent compositions PROCTER & GAMBLE (US) 1998-12-09 CN disclosed
EP-0862607-A1 DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-09-09 EP disclosed
EP-0809490-A1 USE OF LCK SH2 SPECIFIC COMPOUNDS TO TREAT AUTOIMMUNE DISEASES AND ALLOGRAFT REJECTION SMITHKLINE BEECHAM CORPORATION (US) 1997-12-03 EP disclosed
CN-1150451-A Detergent containing heavy metal sequestrant and delayed release peroxyacid bleach system PROCTER & GAMBLE (US) 1997-05-21 CN disclosed
CN-1150454-A Detergents containing surfactant and delayed release enzyme PROCTER & GAMBLE (US) 1997-05-21 CN disclosed
CN-1150455-A Detergents containing enzyme and delayed release peroxyacid bleaching system PROCTER & GAMBLE (US) 1997-05-21 CN disclosed
WO-1997003158-A1 DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-01-30 WO disclosed
EP-0727211-A1 Use of src SH2 specific compounds to treat a bone resorption disease SMITHKLINE BEECHAM CORPORATION (US) 1996-08-21 EP disclosed
WO-1996024343-A1 USE OF LCK SH2 SPECIFIC COMPOUNDS TO TREAT AUTOIMMUNE DISEASES AND ALLOGRAFT REJECTION SMITHKLINE BEECHAM CORPORATION (US) 1996-08-15 WO disclosed