SCHEMBL474925

SCHEMBL474925

C=CCc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
HPGD P15428 4/20 0.57
LMNA P02545 3/20 0.57
SRD5A2 P31213 3/20 0.52
L3MBTL1 Q9Y468 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
CYP3A4 P08684 1/20 0.50
ELANE P08246 1/20 0.49
ATM Q13315 2/20 0.47
RAB9A P51151 3/20 0.46
MAPT P10636 2/20 0.46
MAPK13 O15264 1/20 0.46
MAPK12 P53778 1/20 0.46
MAPK11 Q15759 1/20 0.46
MAPK14 Q16539 1/20 0.46
AKT1 P31749 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL28230348 0.94 ALDH1A1 (0.56) ALDH1A1HPGDLMNASRD5A2L3MBTL1
SCHEMBL1081804 0.92 CYP1A2 (0.47) ALDH1A1HPGDLMNASRD5A2L3MBTL1
SCHEMBL11568621 0.89 SRD5A2 (0.58) ALDH1A1HPGDLMNASRD5A2L3MBTL1
SCHEMBL10429624 0.84 AKR1C3 (0.59) ALDH1A1HPGDLMNAL3MBTL1ATM
SCHEMBL8060229 0.84 CYP3A4 (0.45) ALDH1A1HPGDLMNAL3MBTL1MEN1
SCHEMBL4327902 0.84 ALDH1A1 (0.58) ALDH1A1HPGDLMNASRD5A2L3MBTL1
SCHEMBL11648740 0.84 L3MBTL1 (0.57) ALDH1A1HPGDLMNASRD5A2L3MBTL1
SCHEMBL8329694 0.83 ALDH1A1 (0.59) ALDH1A1HPGDLMNASRD5A2L3MBTL1
SCHEMBL17444458 0.82 MEN1 (0.46) ALDH1A1HPGDLMNAL3MBTL1MEN1
SCHEMBL714706 0.82 ALDH1A1 (0.54) ALDH1A1SRD5A2L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN claimed
US-20230004023-A1 DIFFRACTIVE CONTACT LENSES ALCON INC. (CH) 2023-01-05 US claimed
WO-2022263994-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-12-22 WO claimed
EP-0362649-B1 Radiation-sensitive compositions and their use BASF AG (DE) 1994-03-02 EP claimed
US-5284734-A Insulating layers and printed circuits; precursors for polyimides and polyquinazolines BASF AKTIENGESELLSCHAFT (DE) 1994-02-08 US claimed
EP-0362644-B1 RADIATION-SENSITIVE COMPOSITIONS AND THEIR USE BASF Aktiengesellschaft (DE) 1993-05-26 EP claimed
US-5087550-A Polymer procursor and aryl-containing carbonyl compounds BASF AKTIENGESELLSCHAFT (DE) 1992-02-11 US claimed
EP-0362649-A2 Radiation-sensitive compositions and their use BASF Aktiengesellschaft (DE) 1990-04-11 EP claimed
EP-0362644-A1 Radiation-sensitive compositions and their use BASF Aktiengesellschaft (DE) 1990-04-11 EP claimed
WO-2026105013-A1 CONTACT LENSES WITH COLOR FILTERING ZONE ALCON INC. (CH) 2026-05-21 WO disclosed
US-20260133439-A1 CONTACT LENSES WITH COLOR FILTERING ZONE ALCON INC. (CH) 2026-05-14 US disclosed
US-20260118700-A1 DIFFRACTIVE MULTIFOCAL CONTACT LENS ALCON INC (CH) 2026-04-30 US disclosed
US-20260104598-A1 COMPOSITE CONTACT LENSES WITH ULTRATHIN OBJECTS ALCON INC (CH) 2026-04-16 US disclosed
EP-0362649-A2 Radiation-sensitive compositions and their use BASF Aktiengesellschaft (DE) 1990-04-11 EP disclosed
EP-0355028-A1 Method for preventing weathering of mineral substrates BASF Aktiengesellschaft (DE) 1990-02-21 EP disclosed
EP-0343467-A2 Hot melt adhesives cross-linkable in the air, using ultraviolet radiation BASF Aktiengesellschaft (DE) 1989-11-29 EP disclosed
EP-0339522-A2 By UV-radiation crosslinkable composition for the preparation of adhering coatings BASF Aktiengesellschaft (DE) 1989-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260133439-A1 CONTACT LENSES WITH COLOR FILTERING ZONE MYO1G, STRA6, GJA1 ALDH1A1 2727/4885HPGD 3706/4885LMNA 703/4885
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA ALDH1A1 1323/4885HPGD 2881/4885LMNA 531/4885
US-20260104598-A1 COMPOSITE CONTACT LENSES WITH ULTRATHIN OBJECTS CRYZ, CRYAA, LIMA1 ALDH1A1 1922/4885HPGD 4462/4885LMNA 626/4885
US-20260118700-A1 DIFFRACTIVE MULTIFOCAL CONTACT LENS DSG1, SDC1, DSP ALDH1A1 3575/4885HPGD 4557/4885LMNA 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.