Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.66 |
| ▸ | HTR2A | P28223 | 5/20 | 0.56 |
| ▸ | HTR2C | P28335 | 5/20 | 0.56 |
| ▸ | HTR2B | P41595 | 5/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329871 | 0.79 | KDM1A (0.66) | KDM1AHTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL15372957 | 0.79 | KDM1A (0.66) | KDM1AHTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL20187237 | 0.79 | KDM1A (1.00) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL15096161 | 0.79 | KDM1A (1.00) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| Hydrochloric Acid SCHEMBL16340510 | 0.78 | KDM1A (1.00) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| Hydrochloric Acid SCHEMBL17766516 | 0.78 | KDM1A (1.00) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL149599 | 0.73 | KDM1A (0.58) | KDM1AHTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL22335081 | 0.73 | HTR2C (0.68) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL30016116 | 0.73 | KDM1A (0.58) | KDM1AHTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL29134399 | 0.73 | KDM1A (0.58) | KDM1AHTR2AHTR2CHTR2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |