Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.58 |
| ▸ | HTR2A | P28223 | 5/20 | 0.50 |
| ▸ | HTR2C | P28335 | 5/20 | 0.50 |
| ▸ | HTR2B | P41595 | 5/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957178 | 0.79 | HTR2C (0.50) | KDM1AHTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL29954593 | 0.79 | HTR2A (0.51) | KDM1AHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL1722128 | 0.77 | MAOB (0.48) | KDM1AHTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL29954166 | 0.77 | MAOB (0.48) | KDM1AHTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL1781688 | 0.77 | MAOB (0.48) | KDM1AHTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL29955006 | 0.75 | HTR2C (0.55) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL15096161 | 0.73 | KDM1A (1.00) | KDM1AHTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL20187237 | 0.73 | KDM1A (1.00) | KDM1AHTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL8329871 | 0.73 | KDM1A (0.66) | KDM1AHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL8329869 | 0.73 | KDM1A (0.66) | KDM1AHTR2AHTR2CHTR2BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732102-B2 | System for controlling the reactivity of boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-08-15 | — | — | US | disclosed |
| US-20170002026-A1 | System for Controlling the Reactivity of Boronic Acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2017-01-05 | — | — | US | disclosed |
| US-9328127-B2 | System for controlling the reactivity of boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-05-03 | — | — | US | disclosed |
| EP-2181103-B1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | UNIV ILLINOIS (US) | 2015-08-05 | — | — | EP | disclosed |
| CN-101754959-B | System for controlling reactivity of boronic acids | UNIV ILLINOIS | 2014-05-14 | — | — | CN | disclosed |
| US-20130296573-A1 | System for Controlling the Reactivity of Boronic Acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-11-07 | — | — | US | disclosed |
| US-8318983-B2 | System for controlling the reactivity of boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-11-27 | — | — | US | disclosed |
| US-20120059184-A1 | System for Controlling the Reactivity of Boronic Acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-03-08 | — | — | US | disclosed |
| US-8013203-B2 | System for controlling the reactivity of boronic acids | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-09-06 | — | — | US | disclosed |
| CN-101754959-A | The system of control acid reaction | UNIV ILLINOIS | 2010-06-23 | — | — | CN | disclosed |
| EP-2181103-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | The Board Of Trustees Of The University Of Illinois (US) | 2010-05-05 | — | — | EP | disclosed |
| US-20090030238-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-01-29 | — | — | US | disclosed |
| WO-2009014550-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2009-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170002026-A1 | System for Controlling the Reactivity of Boronic Acids | ORC3, BRS3, OSBPL3 | KDM1A 4064/4885HTR2A 4586/4885HTR2C 4528/4885 |
| US-20120059184-A1 | System for Controlling the Reactivity of Boronic Acids | ORC3, BRS3, OSBPL3 | KDM1A 4064/4885HTR2A 4586/4885HTR2C 4528/4885 |
| US-20130296573-A1 | System for Controlling the Reactivity of Boronic Acids | ORC3, BRS3, OSBPL3 | KDM1A 4064/4885HTR2A 4586/4885HTR2C 4528/4885 |
| US-20090030238-A1 | SYSTEM FOR CONTROLLING THE REACTIVITY OF BORONIC ACIDS | ORC3, BRS3, OSBPL3 | KDM1A 4064/4885HTR2A 4586/4885HTR2C 4528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.