Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 13/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327170 | 0.89 | MAPT (0.55) | GAASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL8323053 | 0.88 | MAPT (0.54) | GAASMN1; SMN2MAPT | |
| SCHEMBL8329674 | 0.83 | MAPT (0.43) | DHODHSMN1; SMN2P2RX3MAPT | |
| SCHEMBL8327174 | 0.82 | P2RX3 (0.43) | P2RX3 | |
| SCHEMBL8328406 | 0.77 | PDE10A (0.46) | GAAP2RX3IGF1RMAPTPDE10A | |
| Hydrochloric Acid SCHEMBL8327918 | 0.75 | PDE10A (0.47) | P2RX3IGF1RPDE10A | |
| SCHEMBL8328461 | 0.75 | MAPT (0.52) | GAASMN1; SMN2MAPT | |
| SCHEMBL8327738 | 0.74 | MAPT (0.41) | DHODHSMN1; SMN2P2RX3MAPTPDE10A | |
| Hydrochloric Acid SCHEMBL8328640 | 0.74 | MAPT (0.51) | GAASMN1; SMN2MAPT | |
| SCHEMBL8321309 | 0.74 | PDE4B (0.61) | GAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |
| EP-0705260-A1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-04-10 | — | — | EP | claimed |