Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CTRC | Q99895 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26613603 | 0.87 | CHEK2 (0.49) | RARBRARGALDH1A1GAAKDM4E | |
| SCHEMBL29746186 | 0.87 | CHEK2 (0.49) | RARBRARGALDH1A1GAAKDM4E | |
| SCHEMBL10147842 | 0.84 | CYP1A2 (0.59) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL1289517 | 0.83 | ESR1 (0.73) | RARBRARGALDH1A1KDM4EESR1 | |
| SCHEMBL1289684 | 0.81 | KDM4E (0.60) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL29692924 | 0.80 | PSMB5 (0.57) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL8830006 | 0.80 | PSMB5 (0.57) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL29746225 | 0.80 | KDM4E (0.57) | RARBRARGALDH1A1GAAKDM4E | |
| SCHEMBL4129028 | 0.80 | KDM4E (0.57) | RARBRARGALDH1A1GAAKDM4E | |
| SCHEMBL8321335 | 0.79 | ALDH1A1 (0.79) | ALDH1A1KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709377-B1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS CO LTD (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-5780634-A | Process for producing 2-(carboxyphenyl)-4-quinolinecarboxylic acid compounds | THE GREEN CROSS CORPORATION (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0709377-A1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS COMPANY LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |