Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18169552 | 0.98 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| Ammonia Solution, Strong SCHEMBL29556495 | 0.95 | TSHR (0.48) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL18279915 | 0.91 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL19197808 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL8965833 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL4257584 | 0.83 | THRB (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL962842 | 0.82 | TSHR (0.48) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL3680400 | 0.82 | TSHR (0.48) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1371111 | 0.82 | TSHR (0.48) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL57880 | 0.81 | TSHR (0.52) | TSHRTHRBALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952405-A | A GRAFT COPOLYMER OF POLYLACTIDE OR POLYGLYCOLIDE WITH ADDITION POLYMER SELECTED FROM C2-C8 ALKYL ACRYLATE OR METHACRYLATE, ETHYLENE, VINYL ACETATE, HYDROXYALKYL ACRYLATE OR METHACRYLATE; TACKIFIER, PLASTICIZER, STABILIZER AND WAX | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1999-09-14 | — | — | US | disclosed |
| EP-0899284-A1 | Process for making lactide graft copolymers | National Starch and Chemical Investment Holding Corporation (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0899274-A1 | Lactide graft copolymers and hot melt adhesives prepared from same | National Starch and Chemical Investment Holding Corporation (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5852117-A | Process for making lactide graft copolymers | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1998-12-22 | — | — | US | disclosed |