Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.63 |
| ▸ | XIAP | P98170 | 2/20 | 0.53 |
| ▸ | F7 | P08709 | 6/20 | 0.43 |
| ▸ | F3 | P13726 | 6/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 4/20 | 0.40 |
| ▸ | MME | P08473 | 3/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792002 | 0.92 | GHSR (0.75) | GHSRXIAPF7F3F2 | |
| SCHEMBL8330629 | 0.85 | GHSR (0.75) | GHSRXIAPF7F3F2 | |
| SCHEMBL7794384 | 0.84 | GHSR (0.67) | GHSRXIAPF7F3F2 | |
| SCHEMBL7791979 | 0.84 | GHSR (0.76) | GHSRXIAPF7F3F2 | |
| SCHEMBL8333260 | 0.84 | GHSR (0.66) | GHSRXIAPF7F3F2 | |
| SCHEMBL7795973 | 0.83 | GHSR (0.63) | GHSRXIAPF7F3F2 | |
| SCHEMBL7791808 | 0.83 | GHSR (0.63) | GHSRXIAPF7F3F2 | |
| SCHEMBL7794697 | 0.83 | GHSR (0.65) | GHSRXIAPF7F3F2 | |
| SCHEMBL7795732 | 0.83 | GHSR (0.65) | GHSRXIAPF7F3F2 | |
| SCHEMBL7795532 | 0.82 | GHSR (0.61) | GHSRXIAPF7F3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968924-A | HAVE THE ABILITY TO STIMULATE THE RELEASE OF NATURAL OR ENDOGENOUS GROWTH HORMONE; TREATMENT OF OBESITY, OSTEOPOROSIS | MERCK & CO., INC. (US) | 1999-10-19 | — | — | US | disclosed |