Paraben

Paraben

SCHEMBL8330259

O=C(O)c1ccc(O)cc1.O=[N+]([O-])C(Br)(CO)CO

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
CA2 P00918 4/20 0.53
CA1 P00915 3/20 0.53
CA12 O43570 1/20 0.53
CA3 P07451 1/20 0.53
TYR P14679 1/20 0.53
DRD1 P21728 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
CA5B Q9Y2D0 1/20 0.53
SRD5A2 P31213 2/20 0.48
TDP1 Q9NUW8 2/20 0.46
FBP1 P09467 1/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paraben SCHEMBL9194441 0.81 CA2 (0.59) CA2CA1CA12CA3TYR
SCHEMBL8330261 0.78 ESR1 (0.46) LMNACA2CA1CA12CA7
Paraben SCHEMBL28513211 0.78 CA2 (0.73) LMNACA2CA1CA12CA3
Paraben SCHEMBL1375180 0.76 CA2 (0.70) LMNACA2CA1CA12CA3
Paraben SCHEMBL1373274 0.76 CA2 (0.70) LMNACA2CA1CA12CA3
Paraben SCHEMBL11483689 0.76 CA2 (0.70) LMNACA2CA1CA12CA3
Paraben SCHEMBL28403919 0.76 CA2 (0.70) LMNACA2CA1CA12CA3
Bronopol SCHEMBL23260 0.75
Paraben SCHEMBL9464608 0.73 CA2 (0.80) LMNACA2CA1CA12CA3
Terephthalic Acid SCHEMBL27317317 0.73 CA2 (0.80) LMNACA2CA1CA12CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190262494-A1 TOPICAL DRESSING COMPOSITION FOR THE TREATMENT OF DAMAGED SKIN TISSUE KHORAKIWALA, Habil F (IN) 2019-08-29 US disclosed
US-20190167763-A1 TOPICAL PHARMACEUTICAL COMPOSITION FOR PROMOTING HAIR GROWTH AND/OR REDUCING HAIR LOSS KHORAKIWALA, Habil F (IN) 2019-06-06 US disclosed
US-5872111-A TOILET BAR SOAP, FACIAL BODY CLEANSER, SHAMPOO, CONDITIONER, COSMETIC,SHAVING CREAM OR LOTION, SHOWER GEL, FABRIC SOFTENING CONDITIONER, AND UNDERARM DEODORANT/ANTI-PERSPIRANT LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1999-02-16 US disclosed
EP-0550281-B1 Compositions comprising nonionic glycolipid surfactants UNILEVER PLC (GB) 1997-03-19 EP disclosed
US-5560872-A DETERGENTS; BIODEGRADABLE; GOOD SOLUBILITY LEVER BROTHERS COMPANY (US) 1996-10-01 US disclosed
EP-0729452-A1 ISETHIONATE ESTERS OF ALKYL ALKOXY CARBOXYLIC ACIDS AS MILD SURFACTANTS UNILEVER N.V. (NL) 1996-09-04 EP disclosed
US-5529768-A HAVING NONIONIC AND ANIONIC SURFACTANT CHARACTERISTICS LEVER BROTHERS COMPANY (US) 1996-06-25 US disclosed
EP-0550276-B1 Compositions comprising anionic glycolipid surfactants UNILEVER PLC (GB) 1996-05-08 EP disclosed
US-5505938-A HAVING BOTH ANIONIC AND NONIONIC SURFACTANT CHARACTERISTICS; BIODEGRADABLE LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1996-04-09 US disclosed
US-5466396-A Isethionate esters of alkyl alkoxy carboxylic acid LEVER BROTHERS COMPANY (US) 1995-11-14 US disclosed
EP-0371803-B1 TOPICAL COMPOSITION UNILEVER PLC (GB) 1992-11-11 EP disclosed
US-5139781-A And a cationic cellulose polymer to enhance mildness; for applying to hair or skin CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1992-08-18 US disclosed
EP-0493927-A1 Phosphate esters and compositions containing them UNILEVER PLC (GB) 1992-07-08 EP disclosed
US-5093112-A Hair and skin cleansers CHESEBROUGH-POND'S U.S.A. CO., DIVISION OF CONOPCO, INC. (US) 1992-03-03 US disclosed
US-5078991-A Shampoo or soap containing dialkyl or dialkenyl phosphate, nonirritating CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1992-01-07 US disclosed
EP-0437347-A1 Topical composition UNILEVER PLC (GB) 1991-07-17 EP disclosed
EP-0371803-A1 Topical composition UNILEVER PLC (GB) 1990-06-06 EP disclosed
EP-0371801-A1 Topical composition UNILEVER PLC (GB) 1990-06-06 EP disclosed
EP-0371802-A1 Topical composition UNILEVER PLC (GB) 1990-06-06 EP disclosed
EP-0371804-A1 Topical composition UNILEVER PLC (GB) 1990-06-06 EP disclosed