Paraben

Paraben

SCHEMBL9464608

O=C(O)c1ccc(O)cc1.OCCO

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.80
CA1 P00915 2/20 0.80
CA12 O43570 1/20 0.80
CA3 P07451 1/20 0.80
TYR P14679 1/20 0.80
DRD1 P21728 1/20 0.80
CA4 P22748 1/20 0.80
CA6 P23280 1/20 0.80
CA5A P35218 1/20 0.80
CA7 P43166 1/20 0.80
CA9 Q16790 1/20 0.80
CA14 Q9ULX7 1/20 0.80
CA5B Q9Y2D0 1/20 0.80
SRD5A2 P31213 2/20 0.70
TSHR P16473 2/20 0.60
TP53 P04637 1/20 0.60
ALDH1A1 P00352 3/20 0.58
BLM P54132 2/20 0.58
KDM4E B2RXH2 1/20 0.58
ABL1 P00519 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paraben SCHEMBL3365205 1.00 CA2 (0.80) CA2CA1CA12CA3TYR
Terephthalic Acid SCHEMBL27317317 1.00 CA2 (0.80) CA2CA1CA12CA3TYR
Paraben SCHEMBL28303722 0.93 CA2 (0.70) CA2CA1CA12CA3TYR
Paraben SCHEMBL2880234 0.91 CA2 (0.73) CA2CA1CA12CA3TYR
Terephthalic Acid SCHEMBL17727576 0.91 CA12 (0.65) CA2CA1CA12CA3TYR
Terephthalic Acid SCHEMBL6692916 0.89 CA2 (1.00) CA2CA1CA12CA3TYR
Terephthalic Acid SCHEMBL3460105 0.89 CA2 (1.00) CA2CA1CA12CA3TYR
Paraben SCHEMBL5311518 0.89 CA2 (1.00) CA2CA1CA12CA3TYR
Paraben SCHEMBL20500516 0.89 CA2 (1.00) CA2CA1CA12CA3TYR
Paraben SCHEMBL4110 0.89 CA2 (1.00) CA2CA1CA12CA3TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105828825-A TREATMENT OF INFLAMMATORY LESIONS OF ROSACEA WITH IVERMECTIN 高德美国际公司 2016-08-03 CN claimed
CN-101088114-A Window material for display MITSUI CHEMICALS INC (JP) 2007-12-12 CN disclosed
CN-1313517-C Polyester composition, film made thereof, and magnetic recording medium TORAY INDUSTRIES (JP) 2007-05-02 CN disclosed
CN-1336942-A Polyester composition, film made thereof, and magnetic recording medium TORAY INDUSTRIES (JP) 2002-02-20 CN disclosed
US-5252583-A Isoquinoline derivatives for the treatment of glaucoma or ocular hypertension NISSHIN FLOUR MILLING CO., LTD. (JP) 1993-10-12 US disclosed