Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967844 | 0.82 | SPHK2 (0.46) | SPHK2SPHK1CARM1PRMT6 | |
| SCHEMBL10462905 | 0.80 | SPHK2 (0.50) | SPHK2SPHK1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL8327242 | 0.79 | SPHK2 (0.49) | SPHK2SPHK1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL16225834 | 0.78 | MEN1 (0.55) | SPHK2SPHK1OPRK1 | |
| SCHEMBL8325845 | 0.78 | SPHK2 (0.45) | SPHK2SPHK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9148606 | 0.77 | SPHK2 (0.51) | SPHK2SPHK1 | |
| SCHEMBL9148614 | 0.77 | SPHK2 (0.51) | SPHK2SPHK1 | |
| SCHEMBL9892993 | 0.77 | MAPK1 (0.55) | SPHK2SPHK1ALDH1A1MAPK1CRHBP | |
| SCHEMBL21538565 | 0.76 | CARM1 (0.47) | CARM1PRMT6TAAR1 | |
| SCHEMBL8325593 | 0.75 | SPHK2 (0.41) | SPHK2SPHK1ALDH1A1MAPK1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |