Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.46 |
| ▸ | CCR2 | P41597 | 2/20 | 0.46 |
| ▸ | VEGFA | P15692 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21538565 | 0.91 | CARM1 (0.47) | CARM1PRMT6 | |
| SCHEMBL11462791 | 0.85 | CCR2 (0.49) | SPHK2SPHK1CCR2 | |
| SCHEMBL8330331 | 0.82 | SPHK2 (0.45) | SPHK2SPHK1CARM1PRMT6 | |
| SCHEMBL11199979 | 0.81 | SPHK2 (0.50) | SPHK2SPHK1VEGFAEGLN1FAAH | |
| SCHEMBL7454601 | 0.81 | OPRD1 (0.52) | CCR2OPRD1 | |
| SCHEMBL30150926 | 0.81 | SPHK2 (0.54) | SPHK2SPHK1OPRD1 | |
| SCHEMBL24200095 | 0.80 | SPHK2 (0.49) | SPHK2SPHK1VEGFAEGLN1OPRD1 | |
| SCHEMBL16416519 | 0.80 | VEGFA (0.64) | SPHK2SPHK1VEGFAEGLN1 | |
| SCHEMBL14395220 | 0.80 | MAPK1 (0.54) | SPHK2SPHK1OPRD1FAAH | |
| SCHEMBL11990426 | 0.80 | MAPK1 (0.54) | SPHK2SPHK1OPRD1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697015-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | PHARMACIA & UPJOHN COMPANY (US) | 1996-02-21 | — | — | EP | disclosed |
| WO-1994026708-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | THE UPJOHN COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |