Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30494033 | 1.00 | SIGMAR1 (0.51) | SIGMAR1TMEM97EBPHTR1AADRA1B | |
| SCHEMBL25317113 | 1.00 | SIGMAR1 (0.51) | SIGMAR1TMEM97EBPHTR1AADRA1B | |
| Hydrochloric Acid SCHEMBL7324536 | 0.99 | SIGMAR1 (0.50) | SIGMAR1TMEM97EBPHTR1AADRA1B | |
| Hydrochloric Acid SCHEMBL7324525 | 0.99 | SIGMAR1 (0.50) | SIGMAR1TMEM97EBPHTR1AADRA1B | |
| Hydrochloric Acid SCHEMBL7324521 | 0.99 | SIGMAR1 (0.50) | SIGMAR1TMEM97EBPHTR1AADRA1B | |
| SCHEMBL8330431 | 0.89 | SIGMAR1 (0.43) | SIGMAR1TMEM97EBPHTR1AADRA1B | |
| SCHEMBL8330429 | 0.89 | SIGMAR1 (0.43) | SIGMAR1TMEM97EBPHTR1AADRA1B | |
| SCHEMBL7310895 | 0.88 | SIGMAR1 (0.57) | SIGMAR1TMEM97EBPGAAPSEN1 | |
| SCHEMBL6263930 | 0.88 | SIGMAR1 (0.57) | SIGMAR1TMEM97EBPGAAPSEN1 | |
| SCHEMBL11630013 | 0.88 | SIGMAR1 (0.57) | SIGMAR1TMEM97EBPGAAPSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917464-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1999-05-26 | — | — | EP | claimed |
| WO-1998004251-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1998-02-05 | — | — | WO | claimed |
| US-20230364033-A1 | COMPOUNDS FOR TREATING VIRUS INFECTIONS | MELETIOS THERAPEUTICS (FR) | 2023-11-16 | — | — | US | disclosed |
| EP-4213822-A1 | COMPOUNDS FOR TREATING VIRUS INFECTIONS | MELETIOS Therapeutics (FR) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022058533-A1 | COMPOUNDS FOR TREATING VIRUS INFECTIONS | MELETIOS THERAPEUTICS (FR) | 2022-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230364033-A1 | COMPOUNDS FOR TREATING VIRUS INFECTIONS | ACE, HAVCR2, FURIN | SIGMAR1 3429/4885TMEM97 3055/4885EBP 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.