Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP7 | P09237 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP12 | P39900 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | MME | P08473 | 4/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | CPA1 | P15085 | 2/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.53 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410124 | 0.93 | CTSL (0.58) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL9830825 | 0.89 | MME (0.66) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL9830820 | 0.89 | MME (0.66) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL2372439 | 0.87 | CTSL (0.53) | MMP2MMP7MMP9MMECTSL | |
| SCHEMBL19292528 | 0.87 | ACE (0.70) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL17996007 | 0.87 | ACE (0.70) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL15692369 | 0.87 | PSMB5 (0.68) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL2519489 | 0.85 | ACE (0.56) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL2519495 | 0.85 | ACE (0.56) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL25769240 | 0.84 | CTSL (0.66) | ACEMMECTSLCPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737204-A4 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORP (US) | 1999-06-23 | — | — | EP | disclosed |
| EP-0737204-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995015973-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1995-06-15 | — | — | WO | disclosed |