Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 10/20 | 0.53 |
| ▸ | CTSS | P25774 | 6/20 | 0.48 |
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330748 | 0.87 | ACE (0.60) | CTSLCTSSCTSBPSMB5MME | |
| SCHEMBL16468938 | 0.85 | CTSL (0.55) | CTSLCTSSCTSKMME | |
| SCHEMBL7410124 | 0.84 | CTSL (0.58) | CTSLCTSSCTSBPSMB5MME | |
| SCHEMBL1795838 | 0.82 | CTSL (0.60) | CTSLCTSSCTSKMME | |
| SCHEMBL8530975 | 0.82 | CTSL (0.62) | CTSLCTSSCTSKMME | |
| SCHEMBL4957095 | 0.81 | CTSL (0.58) | CTSLCTSSCTSKMME | |
| SCHEMBL8526731 | 0.80 | CTSL (0.57) | CTSLCTSSCTSKCTSBMME | |
| SCHEMBL8529162 | 0.78 | CTSL (0.55) | CTSLCTSSCTSKMME | |
| SCHEMBL20609249 | 0.78 | CTSK (0.73) | CTSLCTSSCTSKCTSB | |
| SCHEMBL20609250 | 0.78 | CTSK (0.73) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3322435-A1 | PHARMACEUTICAL COMPOSITIONS USEFUL FOR THE TREATMENT OF TISSUE INJURY | Medregen, LLC (US) | 2018-05-23 | — | — | EP | disclosed |
| WO-2017011750-A1 | PHARMACEUTICAL COMPOSITIONS USEFUL FOR THE TREATMENT OF TISSUE INJURY | MEDREGEN, LLC (US) | 2017-01-19 | — | — | WO | disclosed |
| EP-3030232-A2 | WOUND HEALING VIA AUTOLOGOUS STEM CELL MOBILIZATION | The Johns Hopkins University (US) | 2016-06-15 | — | — | EP | disclosed |
| WO-2014179266-A2 | WOUND HEALING VIA AUTOLOGOUS STEM CELL MOBILIZATION | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-11-06 | — | — | WO | disclosed |
| EP-2549992-A2 | METHODS OF TREATMENT USING STEM CELL MOBILIZERS | The Johns Hopkins University (US) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011119738-A2 | METHODS OF TREATMENT USING STEM CELL MOBILIZERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-09-29 | — | — | WO | disclosed |