Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.57 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330814 | 0.94 | PTGS1 (0.58) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL9555892 | 0.84 | PTGS2 (0.74) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL30436399 | 0.84 | PTGS2 (0.74) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL1275691 | 0.83 | MMP8 (0.70) | SMN1; SMN2MMP8TDP1MEN1KMT2A | |
| SCHEMBL2746977 | 0.83 | PTGS1 (0.56) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| Hydrochloric Acid SCHEMBL10677191 | 0.81 | MMP8 (0.68) | SMN1; SMN2MMP8TDP1MEN1KMT2A | |
| Ethane SCHEMBL27824026 | 0.81 | MMP8 (0.68) | SMN1; SMN2MMP8TDP1MEN1KMT2A | |
| Methane SCHEMBL28306525 | 0.81 | MMP8 (0.68) | SMN1; SMN2MMP8TDP1MEN1KMT2A | |
| SCHEMBL11460300 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| Dimethylamine SCHEMBL3834248 | 0.81 | PTGS2 (0.72) | PTGS1PTGS2MAPTCXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |