Triaziquone

Triaziquone

SCHEMBL8330857

NC(CCC(=O)O)C(=O)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.47
GRM6 O15303 2/20 0.47
GRM7 Q14831 2/20 0.47
GRM4 Q14833 2/20 0.47
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GSR P00390 1/20 0.47
CYP1A2 P05177 1/20 0.47
GRIK1 P39086 1/20 0.47
GRM5 P41594 1/20 0.47
GRIA1 P42261 1/20 0.47
GRIA2 P42262 1/20 0.47
GRIA3 P42263 1/20 0.47
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47
GRIA4 P48058 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIK2 Q13002 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL9016339 0.86 DNMT1 (0.36) CYP1A2GRIK1GRIA1GRIA2SLC1A3
Triaziquone SCHEMBL4299467 0.84 DNMT1 (0.39) CYP1A2BLMKMT2ADNMT1
Triaziquone SCHEMBL8966034 0.82 PTGS1 (0.37) CYP1A2PMP22KMT2ADNMT1
Triaziquone SCHEMBL23925212 0.81 HTR2A (0.41) CYP1A2DNMT1
Triaziquone SCHEMBL3505984 0.79 DNMT1 (0.37) CYP1A2DNMT1
Triaziquone SCHEMBL18059816 0.78 DNMT1 (0.34) DNMT1
Triaziquone SCHEMBL7913123 0.77 DNMT1 (0.35) DNMT1
Triaziquone SCHEMBL11740964 0.77 NSD2 (0.42) DNMT1
Triaziquone SCHEMBL8926769 0.76 DNMT1 (0.42) CYP1A2BLMKMT2ADNMT1
Triaziquone SCHEMBL322828 0.75 DNMT1 (0.42) CYP1A2BLMKMT2ADNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105861599-A Synthesis method and application of CpG ODNs 李军涛 2016-08-17 CN claimed
CN-105861599-A Synthesis method and application of CpG ODNs 李军涛 2016-08-17 CN disclosed
EP-0869707-A4 HIGH-AFFINITY POTASSIUM UPTAKE TRANSPORTER FROM HIGHER PLANTS UNIV CALIFORNIA (US) 1999-02-03 EP disclosed
EP-0869707-A1 HIGH-AFFINITY POTASSIUM UPTAKE TRANSPORTER FROM HIGHER PLANTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-10-14 EP disclosed
US-5608145-A High-affinity potassium uptake transporter from higher plants THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-03-04 US disclosed
WO-1996005722-A1 HIGH-AFFINITY POTASSIUM UPTAKE TRANSPORTER FROM HIGHER PLANTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-02-29 WO disclosed
US-5185247-A Qualitative or quantitative analysis of glucose, cholesterol, uric acid or lower alcohols in a fluid sample by contacting with a reagent containing an oxidase, an oxidizable chromogen, peroxidase, a buffer and a hydarzine for colorimetric analysis MILES INC. (US) 1993-02-09 US disclosed
US-5116729-A Hydrazide MILES INC. (US) 1992-05-26 US disclosed
EP-0386562-A2 Stabilization of oxidase enzyme-based test strips Bayer Corporation (US) 1990-09-12 EP disclosed