Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046841 | 0.80 | TSHR (0.41) | TSHRMAPTRECQLALDH1A1PPM1B | |
| SCHEMBL3942273 | 0.79 | TSHR (0.40) | TSHRMAPTRECQLALDH1A1PPM1B | |
| SCHEMBL3942274 | 0.79 | TSHR (0.40) | TSHRMAPTRECQLALDH1A1PPM1B | |
| SCHEMBL9219742 | 0.77 | CYP4F2 (0.40) | TSHRALDH1A1PPM1BPTPN1PPP1CC | |
| SCHEMBL10486329 | 0.74 | CYP4F2 (0.38) | TSHRALDH1A1PPM1BPTPN1PPP1CC | |
| SCHEMBL10028034 | 0.74 | ALDH1A1 (0.39) | ALDH1A1PPM1BPTPN1PPP1CCKMT2A | |
| SCHEMBL16370032 | 0.74 | TSHR (0.35) | TSHRMAPTRECQLALDH1A1PPM1B | |
| SCHEMBL8331833 | 0.74 | TSHR (0.36) | TSHRMAPTRECQLALDH1A1PPM1B | |
| SCHEMBL16732122 | 0.73 | ALDH1A1 (0.41) | MAPTALDH1A1POLBCYP4F2CYP4A11 | |
| SCHEMBL4418141 | 0.73 | ALDH1A1 (0.38) | TSHRMAPTALDH1A1PPM1BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |