Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16732122 | 0.98 | ALDH1A1 (0.41) | ALDH1A1FKBP1ACYP4F2CYP4A11THRB | |
| SCHEMBL10486329 | 0.96 | CYP4F2 (0.38) | ALDH1A1FKBP1ACYP4F2CYP4A11THRB | |
| SCHEMBL9219742 | 0.92 | CYP4F2 (0.40) | ALDH1A1CYP4F2CYP4A11THRBKMT2A | |
| SCHEMBL15973848 | 0.91 | PKM (0.36) | ALDH1A1FKBP1ACYP4F2CYP4A11THRB | |
| SCHEMBL15973183 | 0.89 | ALDH1A1 (0.38) | ALDH1A1FKBP1ACYP4F2CYP4A11THRB | |
| SCHEMBL28817661 | 0.87 | CHRM2 (0.43) | ALDH1A1CYP4F2CYP4A11ATMCHRM2 | |
| SCHEMBL16732048 | 0.85 | CHRM2 (0.41) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL10708309 | 0.85 | CYP4F2 (0.36) | ALDH1A1CYP4F2CYP4A11THRBL3MBTL1 | |
| SCHEMBL8329844 | 0.84 | THRB (0.40) | ALDH1A1FKBP1ATHRBATML3MBTL1 | |
| SCHEMBL15910254 | 0.83 | CYP4F2 (0.39) | CYP4F2CYP4A11THRBKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2876118-B1 | METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER | TOHO TITANIUM CO LTD (JP) | 2022-04-06 | — | — | EP | disclosed |
| US-11028052-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2021-06-08 | — | — | US | disclosed |
| EP-3461816-B1 | FIVE-MEMBERED HETEROCYLIC COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-03-24 | — | — | EP | disclosed |
| US-10421727-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2019-09-24 | — | — | US | disclosed |
| EP-3461816-A1 | FIVE-MEMBERED HETEROCYLIC COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2019-04-03 | — | — | EP | disclosed |
| EP-2963065-B1 | PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, CATALYST FOR POLYMERIZING OLEFINS, AND PRODUCTION METHOD FOR POLYMERIZED OLEFINS | TOHO TITANIUM CO LTD (JP) | 2018-04-04 | — | — | EP | disclosed |
| US-20170369447-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED | 2017-12-28 | — | — | US | disclosed |
| US-9840471-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2017-12-12 | — | — | US | disclosed |
| EP-2963063-B1 | PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, CATALYST FOR POLYMERIZING OLEFINS, AND PRODUCTION METHOD FOR POLYMERIZED OLEFINS | TOHO TITANIUM CO LTD (JP) | 2017-06-14 | — | — | EP | disclosed |
| US-9670294-B2 | Method for producing solid catalyst component for use in polymerization of olefin, catalyst for use in polymerization of olefin, and method for producing olefin polymer | TOHO TITANIUM CO., LTD. (JP) | 2017-06-06 | — | — | US | disclosed |
| US-20150166693-A1 | METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER | TOHO TITANIUM CO., LTD. (JP) | 2015-06-18 | — | — | US | disclosed |
| EP-2876118-A1 | METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER | Toho Titanium CO., LTD. (JP) | 2015-05-27 | — | — | EP | disclosed |
| WO-2014130582-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2014-08-28 | — | — | WO | disclosed |
| US-20130150234-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130150234-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-13 | — | — | US | disclosed |
| US-8383540-B2 | Catalyst composition with halo-malonate internal electron donor and polymer from same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-02-26 | — | — | US | disclosed |
| US-8383540-B2 | Catalyst composition with halo-malonate internal electron donor and polymer from same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-02-26 | — | — | US | disclosed |
| WO-2012087535-A1 | CATALYST COMPOSITION WITH HALO-MALONATE INTERNAL ELECTRON DONOR AND POLYMER FROM SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| US-20120157296-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | W. R. GRACE & CO.-CONN. | 2012-06-21 | — | — | US | disclosed |
| US-20120157296-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | W. R. GRACE & CO.-CONN. | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10421727-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPA1 | ALDH1A1 1692/4885FKBP1A 727/4885CYP4F2 2227/4885 |
| US-20170369447-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM7, TRPA1 | ALDH1A1 1692/4885FKBP1A 727/4885CYP4F2 2227/4885 |
| US-11028052-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPA1 | ALDH1A1 1692/4885FKBP1A 727/4885CYP4F2 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.