Dimethylformamide

Dimethylformamide

SCHEMBL8332170

CN(C)C=O.c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.54
AOC3 Q16853 2/20 0.50
SIGMAR1 Q99720 3/20 0.47
ALDH1A1 P00352 3/20 0.46
TSHR P16473 1/20 0.46
KMT2A Q03164 1/20 0.46
FFAR1 O14842 1/20 0.45
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
ALOX5 P09917 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CASP1 P29466 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KCNH2 Q12809 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL14965882 0.84 TP53 (0.64) TAAR1AOC3ALDH1A1TSHRKMT2A
Dimethylformamide SCHEMBL133144 0.82 ATM (0.41) TAAR1AOC3SIGMAR1ALDH1A1KMT2A
Benzyl Bromide SCHEMBL1833786 0.82 ALDH1A1 (0.61) TAAR1AOC3ALDH1A1TSHRKMT2A
Benzyl Alcohol SCHEMBL28205107 0.82 TSHR (0.61) TAAR1AOC3ALDH1A1TSHRKMT2A
(Chloromethyl)Benzene SCHEMBL11863187 0.82 ALDH1A1 (0.43) TAAR1AOC3ALDH1A1TSHRKMT2A
SCHEMBL5526488 0.80 TAAR1 (0.59) TAAR1AOC3SIGMAR1KMT2A
SCHEMBL1300014 0.80 TAAR1 (0.59) TAAR1AOC3SIGMAR1KMT2A
Dimethylformamide SCHEMBL27810984 0.80 ALDH1A1 (0.71) TAAR1AOC3ALDH1A1TSHRKMT2A
Benzyl Bromide SCHEMBL9083018 0.79 TSHR (0.56) TAAR1AOC3ALDH1A1TSHRKMT2A
Biphenyl SCHEMBL27802171 0.77 ALDH1A1 (0.50) TAAR1ALDH1A1TSHRKMT2AALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5969150-A FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES THE ROCKEFELLER UNIVERSITY (US) 1999-10-19 US disclosed