Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Bromide SCHEMBL9083018 | 0.96 | TSHR (0.56) | ALDH1A1TSHRTRPA1CES2CES1 | |
| Benzyl Bromide SCHEMBL438870 | 0.84 | TSHR (0.78) | ALDH1A1TSHRTRPA1CES2CES1 | |
| Dimethylformamide SCHEMBL8332170 | 0.82 | TAAR1 (0.54) | ALDH1A1TSHRAOC3TAAR1KMT2A | |
| Ethylbenzene SCHEMBL14965882 | 0.80 | TP53 (0.64) | ALDH1A1TSHRAOC3TAAR1ADH1B | |
| Benzyl Bromide SCHEMBL28246315 | 0.79 | ALDH1A1 (0.70) | ALDH1A1TSHRTRPA1CES2CES1 | |
| Benzyl Bromide SCHEMBL27306361 | 0.79 | TSHR (0.70) | ALDH1A1TSHRTRPA1CES2CES1 | |
| (Chloromethyl)Benzene SCHEMBL11863187 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRAOC3TAAR1TDP1 | |
| Benzyl Alcohol SCHEMBL28205107 | 0.78 | TSHR (0.61) | ALDH1A1TSHRCES2CES1AOC3 | |
| Benzyl Bromide SCHEMBL26117242 | 0.78 | ALDH1A1 (0.61) | ALDH1A1TSHRTRPA1CES2CES1 | |
| Benzyl Bromide SCHEMBL5757393 | 0.78 | TSHR (1.00) | ALDH1A1TSHRTRPA1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405858-B1 | PROCESS FOR PRODUCING SUGAR CHAIN ASPARAGINE DERIVATIVE | GLYTECH INC (JP) | 2013-01-02 | — | — | EP | disclosed |
| EP-2481746-A1 | Process for producing sugar chain asparagine derivative | Otsuka Chemical Co., Ltd. (JP) | 2012-08-01 | — | — | EP | disclosed |
| US-8158763-B2 | Lipophilic protected, asparagine-linked oligosaccharide derivative containing a fucose in N-acetylglucosamine on nonreducing terminal side | Kajihara, Yasuhiro (JP) | 2012-04-17 | — | — | US | disclosed |
| EP-2322533-A1 | Process for producing sugar chain asparagine derivative | Otsuka Chemical Co., Ltd. (JP) | 2011-05-18 | — | — | EP | disclosed |
| US-20080214798-A1 | Sugar chain asparagine derivatives, sugar chain asparagine, sugar chain and processes for producing these | OTSUKA CHEMCIAL CO., LTD. (JP) | 2008-09-04 | — | — | US | disclosed |
| US-7304148-B2 | Sugar chain asparagine derivatives, sugar chain asparagine, sugar chain, and processes for producing these | OTSUKA CHEMICAL CO., LTD. (JP) | 2007-12-04 | — | — | US | disclosed |
| US-7135566-B2 | Process for producing sugar chain asparagine derivative | OTSUKA CHEMICAL CO., LTD. (JP) | 2006-11-14 | — | — | US | disclosed |
| US-20060228784-A1 | Sugar chain asparagine derivatives, sugar chain asparagine, sugar chain, and processes for producing these | GLYTECH, INC (JP) | 2006-10-12 | — | — | US | disclosed |
| US-20060166929-A1 | Sugar-chain asparagine derivatives and processes for the preparation thereof | OTSUKA CHEMICAL CO., LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1577397-A1 | SUGAR CHAIN ASPARAGINE DERIVATIVES, SUGAR CHAIN ASPARAGINE, SUGAR CHAIN, AND PROCESSES FOR PRODUCING THESE | Kajihara, Yasuhiro (JP) | 2005-09-21 | — | — | EP | disclosed |
| EP-1577316-A1 | SUGAR-CHAIN ASPARAGINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Kajihara, Yasuhiro (JP) | 2005-09-21 | — | — | EP | disclosed |
| US-20040181054-A1 | Process for producing sugar chain asparagine derivative | GLYTECH, INC. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1405858-A1 | PROCESS FOR PRODUCING SUGAR CHAIN ASPARAGINE DERIVATIVE | Otsuka Chemical Holdings Co., Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060228784-A1 | Sugar chain asparagine derivatives, sugar chain asparagine, sugar chain, and processes for producing these | FUT6, B3GNT2, FUT5 | ALDH1A1 2454/4885TSHR 2537/4885TRPA1 4554/4885 |
| US-20060166929-A1 | Sugar-chain asparagine derivatives and processes for the preparation thereof | ASNS, B3GNT2, FUT6 | ALDH1A1 2206/4885TSHR 620/4885TRPA1 4853/4885 |
| US-20080214798-A1 | Sugar chain asparagine derivatives, sugar chain asparagine, sugar chain and processes for producing these | FUT6, B3GNT2, FUT5 | ALDH1A1 2534/4885TSHR 2361/4885TRPA1 4574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.