SCHEMBL8333012

SCHEMBL8333012

Clc1ccc(C=CCc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.54
KCNA3 P22001 3/20 0.49
GRIN1 Q05586 2/20 0.49
GRIN2B Q13224 2/20 0.49
MAPT P10636 1/20 0.46
NLRP3 Q96P20 1/20 0.46
G6PC1 P35575 1/20 0.46
PLAAT3 P53816 1/20 0.44
PLAAT5 Q96KN8 1/20 0.44
PLAAT2 Q9NWW9 1/20 0.44
PLAAT4 Q9UL19 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NFE2L2 Q16236 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
ARG2 P78540 1/20 0.42
AHR P35869 1/20 0.42
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16052780 1.00 MAOB (0.54) MAOBKCNA3GRIN1GRIN2BMAPT
SCHEMBL29804851 1.00 MAOB (0.54) MAOBKCNA3GRIN1GRIN2BMAPT
SCHEMBL1931967 0.92 GRIN1 (0.49) MAOBKCNA3GRIN1GRIN2BMEN1
SCHEMBL1931966 0.92 GRIN1 (0.49) MAOBKCNA3GRIN1GRIN2BMEN1
SCHEMBL3851041 0.90 AHR (0.46) KCNA3MAPTAHR
SCHEMBL10602496 0.90 AHR (0.46) KCNA3MAPTAHR
SCHEMBL13380927 0.86 LTA4H (0.45) MAOBKCNA3GRIN1GRIN2BMAPT
SCHEMBL163963 0.85 MAOB (0.67) MAOBMAPTMEN1KMT2ACA1
SCHEMBL4256257 0.85 MAOB (0.67) MAOBMAPTMEN1KMT2ACA1
SCHEMBL1892917 0.85 MAOB (0.67) MAOBMAPTMEN1KMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112299946-A Method for synthesizing 1, 2-disubstituted olefin by reacting terminal group olefin with sulfoxide 沅江华龙催化科技有限公司 2021-02-02 CN disclosed
US-9709889-B2 Forming conductive metal patterns using thiosulfate copolymers EASTMAN KODAK COMPANY (US) 2017-07-18 US disclosed
US-20160147148-A1 FORMING CONDUCTIVE METAL PATTERNS USING THIOSULFATE COPOLYMERS BANK OF AMERICA, N.A., AS AGENT 2016-05-26 US disclosed
US-9329482-B2 Forming conductive metal patterns using thiosulfate copolymers EASTMAN KODAK COMPANY (US) 2016-05-03 US disclosed
US-20160016860-A1 METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS DUBLIN CITY UNIVERSITY (IE) 2016-01-21 US disclosed
US-20160016860-A1 METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS DUBLIN CITY UNIVERSITY (IE) 2016-01-21 US disclosed
US-20160016860-A1 METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS DUBLIN CITY UNIVERSITY (IE) 2016-01-21 US disclosed
EP-2970347-A1 METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS Dublin City University (IE) 2016-01-20 EP disclosed
US-20150293451-A1 FORMING CONDUCTIVE METAL PATTERNS USING THIOSULFATE COPOLYMERS BANK OF AMERICA, N.A. 2015-10-15 US disclosed
WO-2014140353-A1 METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS DUBLIN CITY UNIVERSITY (IE) 2014-09-18 WO disclosed
EP-0807659-B1 Polyolefin-based composite material and production process therefor SHOWA DENKO KK (JP) 1999-11-03 EP disclosed
US-5939184-A GRAFT OR BLOCK COPOLYMER CONTAINING UNSATURATED CARBOXYLIC ACID OR DERIVATIVES AND LIPOPHILIC INTERSTRATIFIED COMPOUND WITH A TETRAALKYLAMMONIUM CATION INSERTED IN A SWELLABLE STRATIFORM SILICATE; IMPACT STRENGTH, HEAT RESISTANCE SHOWA DENKO K.K. (JP) 1999-08-17 US disclosed
EP-0807659-A1 Polyolefin-based composite material and production process therefor SHOWA DENKO KABUSHIKI KAISHA (JP) 1997-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160016860-A1 METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS DCXR, TECR, PWWP2B MAOB 242/4885KCNA3 4707/4885GRIN1 3866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.