Adipic Acid

Adipic Acid

SCHEMBL8333196

CC(CCO)CC(C)(C)C.O=C(O)CCCCC(=O)O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC18A2SLC6A2SLC6A3

The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.43
FFAR1 O14842 3/20 0.43
FFAR4 Q5NUL3 3/20 0.43
CAMK2A Q9UQM7 1/20 0.41
LMNA P02545 2/20 0.41
GABRP O00591 2/20 0.41
GABRD O14764 2/20 0.41
GABRA1 P14867 2/20 0.41
GABRB1 P18505 2/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
GABRA5 P31644 2/20 0.41
GABRA3 P34903 2/20 0.41
GABRA2 P47869 2/20 0.41
GABRB2 P47870 2/20 0.41
GABRA4 P48169 2/20 0.41
GABRE P78334 2/20 0.41
GABRA6 Q16445 2/20 0.41
GABRG1 Q8N1C3 2/20 0.41
GABRG3 Q99928 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sebacic Acid SCHEMBL28864413 0.98 GPR84 (0.47) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL28328454 0.88 FFAR4 (0.51) GPR84FFAR1FFAR4TSHRAKR1B1
SCHEMBL26106705 0.87 FFAR4 (0.47) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL10940772 0.87 FFAR4 (0.47) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL26111896 0.87 FFAR4 (0.47) GPR84FFAR1FFAR4LMNATSHR
SCHEMBL585178 0.86 MAPT (0.41) FFAR1FFAR4LMNAGABRPGABRD
SCHEMBL8617574 0.84 TSHR (0.33) GPR84FFAR1FFAR4CAMK2AGABRP
Adipic Acid SCHEMBL6131152 0.84 GPR84 (0.54) GPR84FFAR1FFAR4CAMK2ALMNA
Adipic Acid SCHEMBL5665994 0.84 GPR84 (0.54) GPR84FFAR1FFAR4CAMK2ALMNA
Adipic Acid SCHEMBL31157624 0.84 GPR84 (0.54) GPR84FFAR1FFAR4CAMK2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0938537-A1 ENGINE OIL LUBRICANTS FORMED FROM COMPLEX ALCOHOL ESTERS EXXON CHEMICAL PATENTS INC. (US) 1999-09-01 EP disclosed
US-5942475-A Engine oil lubricants formed from complex alcohol esters EXXON CHEMICAL PATENTS INC. (US) 1999-08-24 US disclosed
EP-0880495-A1 HIGH STABILITY AND LOW METALS ESTERS BASED ON 3,5,5-TRIMETHYL-1-HEXANOL EXXON CHEMICAL PATENTS INC. (US) 1998-12-02 EP disclosed
US-5798319-A SYNTHETIC ESTER COMPOSITION EXHIBITING THERMAL AND OXIDATIVE STABILITY EXXON CHEMICAL PATENTS INC. (US) 1998-08-25 US disclosed
US-5750750-A LUBRICANTS FROM THE REACTION OF A POLYOL, A POLYBASIC ACID AND A MONOHYDRIC ALCOHOL; LUBRICANTS; HYDROLYSIS OF THE ESTERIFICATION METAL CATALYST TO PROVIDE METAL-FREE PRODUCT EXXON CHEMICAL PATENTS INC. (US) 1998-05-12 US disclosed
WO-1998010041-A1 ENGINE OIL LUBRICANTS FORMED FROM COMPLEX ALCOHOL ESTERS EXXON CHEMICAL PATENTS INC. (US) 1998-03-12 WO disclosed
WO-1997026238-A1 HIGH STABILITY AND LOW METALS ESTERS BASED ON 3,5,5-TRIMETHYL-1-HEXANOL EXXON CHEMICAL PATENTS INC. (US) 1997-07-24 WO disclosed