Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.66 |
| ▸ | CA12 | O43570 | 6/20 | 0.66 |
| ▸ | CA9 | Q16790 | 6/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.66 |
| ▸ | MAOB | P27338 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | KDR | P35968 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27903487 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| SCHEMBL958685 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| SCHEMBL14424515 | 0.82 | CA12 (0.75) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| SCHEMBL29419327 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| Water SCHEMBL11848480 | 0.81 | ALDH1A1 (0.96) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| SCHEMBL3549905 | 0.79 | KDM4E (0.68) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| SCHEMBL169915 | 0.79 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| Hymecromone SCHEMBL2357040 | 0.79 | HSD17B3 (1.00) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| SCHEMBL10790823 | 0.79 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| SCHEMBL10793869 | 0.79 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AHSD17B3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164595-A | Coumarin derivative, preparation method thereof and application of coumarin derivative as plant pathogenic fungi bacteriostat | 新疆农业大学 | 2023-12-05 | — | — | CN | claimed |
| CN-102846598-A | Application of coumarin in preparing formation inhibitors of advanced glycation end products (AGEs) | GUANGZHOU KANGCHENG PHARMACEUTICAL RES CO LTD | 2013-01-02 | — | — | CN | claimed |
| JP-11092493-A | — | — | None | — | — | JP | disclosed |
| CN-118724856-A | Benzo-alpha-pyrone derivative and preparation method and application thereof | 新疆农业大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-117720496-A | Coumarin compound and preparation method and application thereof | 新疆农业大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-117164595-A | Coumarin derivative, preparation method thereof and application of coumarin derivative as plant pathogenic fungi bacteriostat | 新疆农业大学 | 2023-12-05 | — | — | CN | disclosed |
| EP-2910644-A1 | Method for the diagnosis of neuronal ceroid lipofuscinoses | Steinbeis-Transferzentrum für Biopolymeranalytik und Biomolekül-Massenspektrometrie (DE) | 2015-08-26 | — | — | EP | disclosed |
| CN-102846598-A | Application of coumarin in preparing formation inhibitors of advanced glycation end products (AGEs) | GUANGZHOU KANGCHENG PHARMACEUTICAL RES CO LTD | 2013-01-02 | — | — | CN | disclosed |
| JP-H1192493-A | NEW AROMATIC DERIVATIVE SUBSTITUTED BY RIBOSE, ITS PRODUCTION AND USE THEREOF AS MEDICINAL AGENT | HOECHST MARION ROUSSEL | 1999-04-06 | — | — | JP | disclosed |