Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.64 |
| ▸ | CA12 | O43570 | 7/20 | 0.64 |
| ▸ | CA9 | Q16790 | 7/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | KDR | P35968 | 1/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29419327 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| SCHEMBL14424515 | 0.81 | CA12 (0.75) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| SCHEMBL958685 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| Water SCHEMBL11848480 | 0.79 | ALDH1A1 (0.96) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| SCHEMBL8333261 | 0.79 | ALDH1A1 (0.70) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| Hymecromone SCHEMBL27728511 | 0.79 | HSD17B3 (0.93) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| SCHEMBL3549905 | 0.78 | KDM4E (0.68) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| Hymecromone SCHEMBL2357040 | 0.78 | HSD17B3 (1.00) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| SCHEMBL10790823 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AHSD17B3CA12 | |
| SCHEMBL10793869 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AHSD17B3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109593084-B | Prolyl hydroxylase small-molecule photosensitive prodrug and preparation method and application thereof | 中国药科大学 | 2021-09-28 | — | — | CN | claimed |
| EP-1073764-A4 | MEMBRANE-PERMEANT PHOSPHOINOSITIDES | UNIV CALIFORNIA (US) | 2001-11-14 | — | — | EP | claimed |
| EP-1073764-A1 | MEMBRANE-PERMEANT PHOSPHOINOSITIDES | The Regents of the University of California (US) | 2001-02-07 | — | — | EP | claimed |
| WO-1999055903-A1 | MEMBRANE-PERMEANT PHOSPHOINOSITIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-11-04 | — | — | WO | claimed |
| US-5955453-A | Membrane-permeant phosphoinositides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-09-21 | — | — | US | claimed |
| US-20230346943-A1 | SPACER-MEDIATED CONTROL OF UNCAGING PHOTOCAGED MOLECULES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2023-11-02 | — | — | US | disclosed |
| WO-2023049826-A1 | GENETICALLY ENCODED VOLTAGE INDICATORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-03-30 | — | — | WO | disclosed |
| US-20220411790-A1 | A CRISPR-CAS9 PLATFORM WITH AN INTRINSIC OFF-SWITCH AND ENHANCED SPECIFICITY | THE JOHNS HOPKINS UNIVERSITY | 2022-12-29 | — | — | US | disclosed |
| US-20220218661-A1 | COMPOSITIONS AND METHODS FOR MODULAR CONTROL OF BIOORTHOGONAL LIGATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-07-14 | — | — | US | disclosed |
| US-11129790-B2 | Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates | NORTHEASTERN UNIVERSITY (US) | 2021-09-28 | — | — | US | disclosed |
| WO-2021150621-A1 | SPACER-MEDIATED CONTROL OF UNCAGING PHOTOCAGED MOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-07-29 | — | — | WO | disclosed |
| WO-2021081468-A1 | A CRISPR-CAS9 PLATFORM WITH AN INTRINSIC OFF-SWITCH AND ENHANCED SPECIFICITY | THE JOHNS HOKINS UNIVERSITY (US) | 2021-04-29 | — | — | WO | disclosed |
| EP-1565578-A2 | RNAI-BASED SENSORS, CAGED INTERFERING RNAS, AND METHODS OF USE THEREOF | Genospectra, Inc. (US) | 2005-08-24 | — | — | EP | disclosed |
| US-20050059028-A1 | RNAi-based sensors, caged interfering RNAs, and methods of use thereof | GENOSPECTRA, INC. | 2005-03-17 | — | — | US | disclosed |
| US-20040166553-A1 | Caged sensors, regulators and compounds and uses thereof | GENOSPECTRA, INC. | 2004-08-26 | — | — | US | disclosed |
| WO-2004045547-A2 | RNAI-BASED SENSORS, CAGED INTERFERING RNAS, AND METHODS OF USE THEREOF | GENOSPECTRA, INC. (US) | 2004-06-03 | — | — | WO | disclosed |
| WO-2004046339-A2 | CAGED SENSORS, REGULATORS AND COMPOUNDS AND USES THEREOF | GENOSPECTRA, INC. (US) | 2004-06-03 | — | — | WO | disclosed |
| EP-1073764-A4 | MEMBRANE-PERMEANT PHOSPHOINOSITIDES | UNIV CALIFORNIA (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-1073764-A1 | MEMBRANE-PERMEANT PHOSPHOINOSITIDES | The Regents of the University of California (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055903-A1 | MEMBRANE-PERMEANT PHOSPHOINOSITIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220218661-A1 | COMPOSITIONS AND METHODS FOR MODULAR CONTROL OF BIOORTHOGONAL LIGATION | CBR3, C1R, CBR1 | ALDH1A1 1613/4885KDM4E 3701/4885KMT2A 1898/4885 |
| US-20230346943-A1 | SPACER-MEDIATED CONTROL OF UNCAGING PHOTOCAGED MOLECULES | DCLRE1A, PCNA, HMBS | ALDH1A1 1218/4885KDM4E 2886/4885KMT2A 1225/4885 |
| US-11129790-B2 | Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates | GLUL, QPCT, DNPEP | ALDH1A1 3701/4885KDM4E 2129/4885KMT2A 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.