Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | CFTR | P13569 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102763 | 0.85 | CFTR (0.49) | GAACFTRMAPTNOTUMLMNA | |
| SCHEMBL7086639 | 0.83 | GAA (0.47) | GAACFTRMAPTNOTUMLMNA | |
| SCHEMBL2476221 | 0.80 | GAA (0.62) | GAAMAPTLMNAHTTKDM4E | |
| SCHEMBL8428710 | 0.79 | MAPT (0.40) | GAAMAPTLMNAHTTMEN1 | |
| SCHEMBL7953912 | 0.79 | MRGPRX4 (0.56) | NOTUMLMNAKDM4EMRGPRX4HPGD | |
| SCHEMBL5107602 | 0.79 | GAA (0.53) | GAAMAPTLMNAHTTKDM4E | |
| SCHEMBL8428714 | 0.79 | SLC9A1 (0.51) | — | |
| Hydrochloric Acid SCHEMBL8335173 | 0.78 | MAPT (0.40) | GAAMAPTLMNAHTTMEN1 | |
| SCHEMBL17110481 | 0.78 | NOTUM (0.55) | GAACFTRMAPTNOTUMLMNA | |
| SCHEMBL17110455 | 0.78 | CFTR (0.56) | GAACFTRMAPTNOTUMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856574-A | ANTIISCHEMIC AGENTS; ANTIARRTHYMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-01-05 | — | — | US | disclosed |