(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL8333767

C(=Cc1ccccc1)c1ccccc1.C=CCc1ccccc1-c1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
DPP4 P27487 1/20 0.46
AKR1B1 P15121 1/20 0.40
KMT2A Q03164 1/20 0.40
PTPN1 P18031 1/20 0.37
PTPN6 P29350 1/20 0.37
MMP9 P14780 1/20 0.37
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
INSR P06213 1/20 0.36
AURKA O14965 1/20 0.36
DAPK3 O43293 1/20 0.36
MAP4K4 O95819 1/20 0.36
RET P07949 1/20 0.36
IGF1R P08069 1/20 0.36
MET P08581 1/20 0.36
PIM1 P11309 1/20 0.36
LTK P29376 1/20 0.36
KDR P35968 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170787 0.91 DPP4 (0.54) GABRA1GABRB2DPP4AKR1B1KMT2A
SCHEMBL27684898 0.89 DPP4 (0.52) GABRA1GABRB2DPP4AKR1B1KMT2A
Biphenyl SCHEMBL7928631 0.89 DPP4 (0.52) GABRA1GABRB2DPP4AKR1B1KMT2A
Water SCHEMBL821345 0.89 DPP4 (0.52) GABRA1GABRB2DPP4AKR1B1KMT2A
SCHEMBL28758160 0.89 DPP4 (0.52) GABRA1GABRB2DPP4AKR1B1KMT2A
SCHEMBL6537109 0.87 GABRA1 (0.59) GABRA1GABRB2DPP4AKR1B1KMT2A
Cyanide SCHEMBL29219587 0.85 GABRA1 (0.48) GABRA1GABRB2DPP4AKR1B1KMT2A
SCHEMBL28267634 0.85 GABRA1 (0.48) GABRA1GABRB2DPP4AKR1B1KMT2A
SCHEMBL27886719 0.85 GABRA1 (0.47) GABRA1GABRB2DPP4AKR1B1KMT2A
SCHEMBL27986059 0.84 GABRA1 (0.47) GABRA1GABRB2DPP4AKR1B1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0848693-A4 ISOMERIZATION OF BISPHENOLS DOW CHEMICAL CO (US) 1999-03-17 EP disclosed
EP-0848693-A1 ISOMERIZATION OF BISPHENOLS THE DOW CHEMICAL COMPANY (US) 1998-06-24 EP disclosed
WO-1997008122-A1 ISOMERIZATION OF BISPHENOLS THE DOW CHEMICAL COMPANY (US) 1997-03-06 WO disclosed