Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803077 | 0.87 | IDO1 (0.49) | IDO1EP300KAT8PLAUPLK1 | |
| SCHEMBL9112765 | 0.85 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL6717206 | 0.84 | SIGMAR1 (0.47) | IDO1EP300KAT8PLK1IMPDH2 | |
| Hydrochloric Acid SCHEMBL8711879 | 0.82 | SIGMAR1 (0.46) | IDO1EP300KAT8PLK1IMPDH2 | |
| SCHEMBL9112697 | 0.82 | CHEK1 (0.41) | IDO1EP300KAT8ALDH1A1CYP3A4 | |
| SCHEMBL6155369 | 0.81 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL6158953 | 0.80 | SIGMAR1 (0.39) | SIGMAR1 | |
| SCHEMBL6154831 | 0.78 | KDM4E (0.40) | IMPDH2IMPDH1ALDH1A1MAPTKDM4E | |
| SCHEMBL9115242 | 0.76 | CTSB (0.40) | ALDH1A1CYP3A4HSD17B10MAPTLMNA | |
| SCHEMBL6720796 | 0.75 | SCN2A (0.36) | SCN2APLK1CDC25BALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | disclosed |