Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | F10 | P00742 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17335896 | 0.86 | F10 (0.50) | S1PR2S1PR1F2F10ALDH1A1 | |
| SCHEMBL17335899 | 0.83 | SLC6A4 (0.53) | PPARAPPARGMAPTCYP3A4CYP1A2 | |
| SCHEMBL5866341 | 0.80 | S1PR2 (0.60) | PPARAPPARGS1PR2S1PR1CYP3A4 | |
| SCHEMBL11038591 | 0.79 | PPARA (0.51) | PPARAPPARGMAPTCYP3A4CYP1A2 | |
| Bromide SCHEMBL5702706 | 0.79 | S1PR2 (0.58) | PPARAPPARGS1PR2S1PR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL5702675 | 0.79 | S1PR2 (0.58) | PPARAPPARGS1PR2S1PR1CYP3A4 | |
| SCHEMBL4467166 | 0.78 | CYP4F2 (0.58) | MAPTCYP4F2CYP4A11CYP3A4CYP1A2 | |
| SCHEMBL2311407 | 0.77 | F2 (0.55) | S1PR2S1PR1F2F10ALDH1A1 | |
| SCHEMBL8903673 | 0.77 | F2 (0.55) | S1PR2S1PR1F2F10ALDH1A1 | |
| SCHEMBL17590526 | 0.77 | CYP4Z1 (0.59) | PPARAMAPTCYP4F2CYP4A11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056750-A1 | CYCLOPENTIL-SUBSTITUTED GLUTARAMIDE COMPOUNDS AS ENDOPEPTIDASE INHIBITORS | PFIZER LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |