Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23291817 | 0.97 | RECQL (0.45) | RECQLKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2901200 | 0.80 | RECQL (0.52) | RECQLKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL1310223 | 0.76 | RECQL (0.48) | RECQLKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10777968 | 0.74 | RECQL (0.57) | RECQLKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL17535294 | 0.74 | RECQL (0.47) | RECQLKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL19542172 | 0.74 | RECQL (0.47) | RECQLKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8838248 | 0.74 | RECQL (0.52) | RECQLKMT2AMEN1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL23291018 | 0.74 | RECQL (0.47) | RECQLKMT2AMEN1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL23290967 | 0.74 | RECQL (0.47) | RECQLKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8335952 | 0.72 | RECQL (0.50) | RECQLKMT2AMEN1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858941-B2 | Heterocyclic and heteroaryl compounds for treating Huntington's disease | PTC THERAPEUTICS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20210238186-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS HD, INC. | 2021-08-05 | — | — | US | disclosed |
| US-5981065-A | ELECTRICAL CONDUCTORS HAVING GREASE FILLED INTERSTICES THEREBETWEEN, EACH ELECTRICAL CONDUCTOR COVERING WITH POLYOLEFINS LAYER AND THE REACTION PRODUCT OF A HINDERED AMINE AMIC ACID HYDRAZIDE, A PHENOL OR AN AMINE HYDRAZIDE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |
| WO-1993024937-A1 | TELEPHONE CABLES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-12-09 | — | — | WO | disclosed |
| EP-0303986-B1 | MULTIPURPOSE POLYMER BOUND STABILIZERS | ATOCHEM NORTH AMERICA, INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| US-5096974-A | Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends | ATOCHEM NORTH AMERICA, INC. (US) | 1992-03-17 | — | — | US | disclosed |
| US-4981915-A | HYDRAZIDE MODIFIERS | ATOCHEM NORTH AMERICA, INC. (US) | 1991-01-01 | — | — | US | disclosed |
| US-4863999-A | IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS | PENNWALT CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0303986-A2 | Multipurpose polymer bound stabilizers | ATOCHEM NORTH AMERICA, INC. (US) | 1989-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858941-B2 | Heterocyclic and heteroaryl compounds for treating Huntington's disease | HTT, HYPK, FH | RECQL 27/4885KMT2A 1133/4885MEN1 1477/4885 |
| US-20210238186-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | HTT, HYPK, FH | RECQL 27/4885KMT2A 1133/4885MEN1 1477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.