Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982442 | 0.99 | MEN1 (0.57) | MEN1KMT2ACYP1A2CYP2C19NOX1 | |
| SCHEMBL4987122 | 0.96 | NOX1 (0.59) | MEN1KMT2ACYP1A2CYP2C19NOX1 | |
| Oxalic Acid SCHEMBL4982635 | 0.94 | NOX1 (0.57) | MEN1KMT2ACYP1A2CYP2C19NOX1 | |
| SCHEMBL4982329 | 0.90 | PDK1 (0.48) | MEN1KMT2ACYP1A2CYP2C19NOX1 | |
| Hydrochloric Acid SCHEMBL4982388 | 0.89 | PDK1 (0.47) | MEN1KMT2ACYP1A2CYP2C19NOX1 | |
| SCHEMBL4983263 | 0.89 | NOX1 (0.58) | MEN1KMT2ACYP1A2CYP2C19NOX1 | |
| SCHEMBL4979740 | 0.83 | NOX1 (0.64) | MEN1KMT2ACYP1A2CYP2C19NOX1 | |
| SCHEMBL4981856 | 0.80 | MEN1 (0.55) | MEN1KMT2ACYP1A2CYP2C19NOX1 | |
| SCHEMBL8331017 | 0.79 | LMNA (0.56) | CYP1A2CYP2C19NOX1RAB9ASMN1; SMN2 | |
| SCHEMBL4979973 | 0.79 | MEN1 (0.69) | MEN1KMT2ACYP1A2CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | disclosed |