Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 18/20 | 0.67 |
| ▸ | MMP2 | P08253 | 16/20 | 0.67 |
| ▸ | MMP9 | P14780 | 14/20 | 0.67 |
| ▸ | MMP1 | P03956 | 13/20 | 0.67 |
| ▸ | MMP14 | P50281 | 13/20 | 0.67 |
| ▸ | MMP8 | P22894 | 12/20 | 0.67 |
| ▸ | MMP3 | P08254 | 10/20 | 0.67 |
| ▸ | MMP7 | P09237 | 1/20 | 0.66 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5919453 | 0.91 | MMP13 (0.62) | MMP13MMP2MMP9MMP1MMP14 | |
| SCHEMBL5919537 | 0.87 | MMP13 (0.65) | MMP13MMP2MMP9MMP1MMP14 | |
| SCHEMBL5919522 | 0.84 | MMP13 (0.61) | MMP13MMP2MMP9MMP1MMP14 | |
| SCHEMBL5919664 | 0.81 | MMP13 (1.00) | MMP13MMP2MMP9MMP1MMP14 | |
| SCHEMBL5919366 | 0.81 | MMP13 (1.00) | MMP13MMP2MMP9MMP1MMP14 | |
| SCHEMBL5919573 | 0.80 | MMP13 (0.80) | MMP13MMP2MMP9MMP1MMP14 | |
| SCHEMBL5919493 | 0.80 | MMP13 (0.80) | MMP13MMP2MMP9MMP1MMP14 | |
| SCHEMBL5919461 | 0.80 | MMP1 (1.00) | MMP13MMP2MMP9MMP1MMP14 | |
| SCHEMBL5919456 | 0.79 | MMP13 (0.61) | MMP13MMP2MMP9MMP1MMP14 | |
| SCHEMBL5919554 | 0.78 | MMP13 (0.67) | MMP13MMP2MMP9MMP1MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043943-A1 | AROMATIC SULFONE HYDROXAMIC ACIDS AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |