Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | DUSP22 | Q9NRW4 | 3/20 | 0.39 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290394 | 0.89 | MEN1 (0.52) | KMT2APOLBMEN1ALDH1A1HSD17B3 | |
| SCHEMBL3899841 | 0.76 | STAT3 (0.63) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL3899838 | 0.76 | STAT3 (0.63) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL13407209 | 0.74 | MYC (0.49) | KMT2APOLBMEN1L3MBTL1 | |
| SCHEMBL13766507 | 0.73 | CISD1 (0.44) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL12177437 | 0.73 | ALDH1A1 (0.58) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL13082002 | 0.72 | KMT2A (0.51) | KMT2APOLBMEN1MAPTPTPN12 | |
| SCHEMBL13081727 | 0.72 | PTPN12 (0.48) | KMT2APOLBMEN1MAPTL3MBTL1 | |
| SCHEMBL13855614 | 0.70 | CISD1 (0.44) | POLBALDH1A1HSD17B3MAPTLMNA | |
| SCHEMBL9983039 | 0.69 | POLB (1.00) | KMT2APOLBMEN1ALDH1A1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043955-A1 | RHODANINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RIGEL PHARMACEUTICALS, INC. (US) | 2004-05-27 | — | — | WO | disclosed |