Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | DUSP22 | Q9NRW4 | 5/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334697 | 0.89 | KMT2A (0.53) | MEN1KMT2APOLBHSD17B3ALDH1A1 | |
| SCHEMBL13766507 | 0.85 | CISD1 (0.44) | MEN1KMT2APOLBALDH1A1DUSP22 | |
| SCHEMBL13002193 | 0.78 | PIK3CG (0.54) | MEN1KMT2ARAB9A | |
| SCHEMBL3896679 | 0.76 | APEX1 (0.66) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL30089282 | 0.76 | APEX1 (0.66) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL3897410 | 0.76 | APEX1 (0.66) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL8337980 | 0.72 | KMT2A (0.49) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL13002189 | 0.71 | KMO (0.46) | MEN1KMT2APOLBALDH1A1KMO | |
| SCHEMBL13436795 | 0.71 | MEN1 (0.54) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL3899838 | 0.69 | STAT3 (0.63) | MEN1KMT2APOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041951-A2 | RHODANINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |