Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | GALR1 | P47211 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829715 | 0.91 | PTPN11 (0.51) | PTPN11PTPN1PTPN6ITGB1ITGA4 | |
| SCHEMBL3994279 | 0.91 | PTPN11 (0.51) | PTPN11PTPN1PTPN6ITGB1ITGA4 | |
| SCHEMBL8337866 | 0.91 | PTPN11 (0.44) | PTPN11PTPN1PTPN6ITGB1ITGA4 | |
| SCHEMBL5926601 | 0.89 | HDAC1 (0.53) | PTPN11PTPN1PTPN6CNR2HDAC1 | |
| SCHEMBL8338624 | 0.84 | LRRK2 (0.49) | KIFC1ABCG2 | |
| SCHEMBL8338729 | 0.84 | KIFC1 (0.49) | KIFC1ABCG2 | |
| SCHEMBL3995215 | 0.81 | PTPN11 (0.46) | PTPN11PTPN1PTPN6ITGB1ITGA4 | |
| SCHEMBL3995245 | 0.81 | CNR2 (0.46) | PTPN11PTPN1PTPN6CNR2HDAC1 | |
| SCHEMBL3994280 | 0.81 | PTPN11 (0.48) | PTPN11PTPN1PTPN6CYSLTR2CYSLTR1 | |
| SCHEMBL8337501 | 0.80 | LRRK2 (0.47) | KIFC1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | disclosed |