Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL834538 | 0.94 | HTR6 (1.00) | HTR6 | |
| SCHEMBL834054 | 0.91 | HTR6 (1.00) | HTR6 | |
| SCHEMBL835964 | 0.90 | HTR6 (1.00) | HTR6 | |
| SCHEMBL836865 | 0.88 | HTR6 (1.00) | HTR6 | |
| SCHEMBL835021 | 0.87 | HTR6 (1.00) | HTR6 | |
| SCHEMBL836443 | 0.87 | HTR6 (1.00) | HTR6 | |
| SCHEMBL836107 | 0.87 | HTR6 (1.00) | HTR6 | |
| SCHEMBL833930 | 0.85 | HTR6 (0.89) | HTR6 | |
| SCHEMBL834050 | 0.85 | HTR6 (0.84) | HTR6 | |
| SCHEMBL834566 | 0.85 | HTR6 (1.00) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143303-B2 | Carbazole derivatives as functional 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2012-03-27 | — | — | US | claimed |
| EP-1948166-B1 | CARBAZOLE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LTD (IN) | 2010-10-20 | — | — | EP | claimed |
| US-20100189646-A1 | Carbazole Derivatives as Functional 5-HT6 Ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-07-29 | — | — | US | claimed |
| US-8143303-B2 | Carbazole derivatives as functional 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2012-03-27 | — | — | US | disclosed |
| EP-1948166-B1 | CARBAZOLE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LTD (IN) | 2010-10-20 | — | — | EP | disclosed |
| US-20100189646-A1 | Carbazole Derivatives as Functional 5-HT6 Ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-07-29 | — | — | US | disclosed |
| EP-1948166-A1 | CARBAZOLE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007046111-A1 | CARBAZOLE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189646-A1 | Carbazole Derivatives as Functional 5-HT6 Ligands | HTR6, HTR5A, HTR3B | HTR6 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.