Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11120007 | 0.62 | HPGD (0.51) | CYP2C19CYP1A2CYP2D6GAAALDH1A1 | |
| SCHEMBL14894166 | 0.61 | GAA (0.71) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10408103 | 0.61 | KMT2A (0.49) | GAAHPGDMEN1KMT2AMMP13 | |
| SCHEMBL11122566 | 0.60 | HPGD (0.49) | CYP2C19CYP1A2CYP2D6GAAALDH1A1 | |
| SCHEMBL27866 | 0.60 | CYP2D6 (0.80) | CYP2C19CYP1A2CYP2D6GAAALDH1A1 | |
| SCHEMBL9315092 | 0.60 | CYP1A2 (1.00) | CYP2C19CYP1A2CYP2D6GAAALDH1A1 | |
| SCHEMBL12838360 | 0.60 | ALDH1A1 (0.71) | CYP2C19CYP1A2CYP2D6GAAALDH1A1 | |
| SCHEMBL30865487 | 0.60 | HPGD (0.77) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL178366 | 0.59 | MAPK14 (0.75) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL1032002 | 0.59 | MAPK1 (0.77) | CYP2C19GAAALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014908-A1 | HETEROBICYLCIC METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |