Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.72 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302673 | 0.93 | MAPK14 (0.75) | MAPK14POLBMEN1KMT2AHDAC6 | |
| SCHEMBL13932522 | 0.91 | ALDH1A1 (0.78) | MAPK14POLBMEN1KMT2AHDAC6 | |
| SCHEMBL11900090 | 0.91 | HDAC6 (0.85) | POLBHDAC6HDAC2HDAC8LMNA | |
| SCHEMBL1927145 | 0.90 | EPHX2 (0.77) | MAPK14POLBMEN1KMT2AHDAC6 | |
| SCHEMBL457082 | 0.87 | HDAC6 (0.79) | HDAC6HDAC2HDAC8LMNARAB9A | |
| SCHEMBL31061058 | 0.86 | MAPK14 (1.00) | MAPK14LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16589429 | 0.86 | HDAC6 (0.72) | POLBHDAC6HDAC2HDAC8LMNA | |
| SCHEMBL6843720 | 0.85 | HDAC6 (0.77) | POLBHDAC6HDAC2HDAC8LMNA | |
| SCHEMBL4747957 | 0.85 | NR1H4 (0.81) | POLBKMT2AHDAC6HDAC2HDAC8 | |
| SCHEMBL15985750 | 0.85 | MAPK14 (0.65) | MAPK14POLBMEN1KMT2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005468-B | Method for synthesizing N-alkylated amide compound by catalyzing alcohols and nitriles with nitrogen-carbon material | 常州大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-118005468-A | Method for synthesizing N-alkylated amide compound by catalyzing alcohols and nitriles with nitrogen-carbon material | 常州大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-115304506-B | Preparation method of secondary amide compound by activating primary amide through boron salt catalysis | 中国人民解放军国防科技大学 | 2023-11-14 | — | — | CN | disclosed |
| US-20230046065-A1 | MERGING C(sp3)-H ACTIVATION WITH DNA-ENCODING | THE SCRIPPS RESEARCH INSTITUTE | 2023-02-16 | — | — | US | disclosed |
| WO-2023015236-A2 | COMPOSITION AND METHOD FOR TREATMENT OF GRAM NEGATIVE BACTERIAL INFECTION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-02-09 | — | — | WO | disclosed |
| CN-115557849-A | Method for synthesizing imide compound under induction of NBS and water by visible light | 西南大学 | 2023-01-03 | — | — | CN | disclosed |
| CN-115304506-A | Preparation method of secondary amide compound by activating primary amide under catalysis of boron salt | 中国人民解放军国防科技大学 | 2022-11-08 | — | — | CN | disclosed |
| WO-2022224212-A1 | GPR35 AGONIST COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-10-27 | — | — | WO | disclosed |
| US-11471868-B2 | Redox dehydration coupling catalysts and methods related thereto | EMORY UNIVERSITY (US) | 2022-10-18 | — | — | US | disclosed |
| EP-4067355-A1 | SPIRO-CONDENSED PYRROLIDINE DERIVATIVES AS DEUBIQUITYLATING ENZYME (DUB) INHIBITORS | Mission Therapeutics Limited (GB) | 2022-10-05 | — | — | EP | disclosed |
| US-20090299098-A1 | Catalytic Metathesis of Secondary Amides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090186875-A1 | Dihydrothienopyrimidines, suitable for the treatment of respiratory, gastrointestinal, inflammatory, nervous system disorders and/or cancer | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-07-23 | — | — | US | disclosed |
| US-20090029990-A1 | Dihydropteridinones in the treatment of respiratory diseases | MAIER UDO | 2009-01-29 | — | — | US | disclosed |
| US-7432292-B2 | Sulfhydantoins as phosphate isosteres | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-10-07 | — | — | US | disclosed |
| CN-101184758-A | Novel compounds | GLAXO GROUP LTD (GB) | 2008-05-21 | — | — | CN | disclosed |
| US-7253158-B2 | Sulfonamides | HOFFMANN-LA ROCHE INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-20070043055-A1 | Dihydropteridinones in the treatment of respiratory diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| US-6958243-B2 | Performing a one-pot organic reaction, which includes carbon monoxide (CO) as reactant and does not use of an external gas source, by contacting a non-catalyzing CO releasing compound such as a metal carbonyl with an energy source | BIOTAGE AB (SE) | 2005-10-25 | — | — | US | disclosed |
| US-20050221389-A1 | Organic reactions with CO generating materials | BIOTAGE AB (SE) | 2005-10-06 | — | — | US | disclosed |
| US-20020161266-A1 | Performing a one-pot organic reaction, which includes carbon monoxide (CO) as reactant and does not use of an external gas source, by contacting a non-catalyzing CO releasing compound such as a metal carbonyl with an energy source | BIOTAGE AB (SE) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186875-A1 | Dihydrothienopyrimidines, suitable for the treatment of respiratory, gastrointestinal, inflammatory, nervous system disorders and/or cancer | DPYD, DHODH, FH | MAPK14 3540/4885POLB 861/4885MEN1 2282/4885 |
| US-20090299098-A1 | Catalytic Metathesis of Secondary Amides | NAAA, NAT1, NAT10 | MAPK14 1283/4885POLB 625/4885MEN1 251/4885 |
| US-20070043055-A1 | Dihydropteridinones in the treatment of respiratory diseases | QDPR, DHPS, NDUFS6 | MAPK14 4305/4885POLB 3804/4885MEN1 1447/4885 |
| US-20050221389-A1 | Organic reactions with CO generating materials | KIT, NOS1, NOS2 | MAPK14 2550/4885POLB 1053/4885MEN1 1563/4885 |
| US-20020161266-A1 | Performing a one-pot organic reaction, which includes carbon monoxide (CO) as reactant and does not use of an external gas source, by contacting a non-catalyzing CO releasing compound such as a metal carbonyl with an energy source | KIT, CBR1, NOS1 | MAPK14 2554/4885POLB 1986/4885MEN1 1233/4885 |
| US-20090029990-A1 | Dihydropteridinones in the treatment of respiratory diseases | QDPR, DHPS, NDUFS6 | MAPK14 4305/4885POLB 3804/4885MEN1 1447/4885 |
| US-11471868-B2 | Redox dehydration coupling catalysts and methods related thereto | SCLY, TST, SQOR | MAPK14 2463/4885POLB 1584/4885MEN1 3987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.