Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 5/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671144 | 1.00 | CASR (0.48) | CASRMETAP2METAP1SSTR4LMNA | |
| SCHEMBL9239748 | 0.91 | ITGB3 (0.50) | CASRMETAP2METAP1SSTR4LMNA | |
| SCHEMBL7671141 | 0.88 | METAP2 (0.48) | CASRMETAP2METAP1SSTR4LMNA | |
| SCHEMBL14304105 | 0.77 | CCR1 (0.61) | FKBP1A | |
| SCHEMBL15665589 | 0.77 | SSTR4 (0.56) | CASRMETAP2METAP1SSTR4LMNA | |
| SCHEMBL15665222 | 0.77 | SSTR4 (0.56) | CASRMETAP2METAP1SSTR4LMNA | |
| SCHEMBL15665657 | 0.77 | SSTR4 (0.56) | CASRMETAP2METAP1SSTR4LMNA | |
| SCHEMBL15665069 | 0.77 | SSTR4 (0.56) | CASRMETAP2METAP1SSTR4LMNA | |
| SCHEMBL15665221 | 0.77 | SSTR4 (0.56) | CASRMETAP2METAP1SSTR4LMNA | |
| SCHEMBL15665071 | 0.77 | SSTR4 (0.56) | CASRMETAP2METAP1SSTR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958949-A | INHIBITORS OF THE ENZYME ACTIVITY ASSOCIATED WITH IMMUNOPHILIN PROTEINS, PARTICULARLY PEPTIDYL-PROLYL ISOMERASE, OR ROTAMASE, ENZYME ACTIVITY; TREATMENT OF NERVOUS SYSTEM DISORDERS | GPI NIL HOLDINGS INC. (US) | 1999-09-28 | — | — | US | disclosed |