Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.57 |
| ▸ | GHSR | Q92847 | 1/20 | 0.55 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.53 |
| ▸ | LIMK2 | P53671 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | IL1RN | P18510 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945926 | 0.80 | GHSR (0.53) | ADRB2ADRB1ADRB3GHSRLIMK1 | |
| SCHEMBL11726442 | 0.79 | TRPV1 (0.46) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL11726228 | 0.79 | TRPV1 (0.46) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL11891712 | 0.78 | FFAR1 (0.66) | ADRB2ADRB1ADRB3GHSRLIMK1 | |
| SCHEMBL11733685 | 0.77 | TRPV1 (0.45) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL28032113 | 0.77 | ALDH1A1 (0.73) | LIMK1LIMK2KMT2AMEN1CA12 | |
| SCHEMBL94910 | 0.76 | NPC1 (0.51) | MAPT | |
| SCHEMBL11256312 | 0.76 | NPC1 (0.51) | MAPT | |
| SCHEMBL21916561 | 0.76 | NPC1 (0.51) | MAPT | |
| SCHEMBL21337225 | 0.76 | NPC1 (0.51) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994398-A | ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 1999-11-30 | — | — | US | disclosed |